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11/18/2016 3:13:00 PM | Browse: 1164 | Download: 1766
Publication Name World Journal of Gastroenterology
Manuscript ID 27964
Country/Territory China
Received
2016-06-23 08:44
Peer-Review Started
2016-06-24 13:09
To Make the First Decision
2016-08-22 15:10
Return for Revision
2016-08-23 08:45
Revised
2016-09-04 20:14
Second Decision
2016-09-21 17:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-28 19:18
Articles in Press
2016-09-28 19:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-10-09 08:35
Typeset the Manuscript
2016-11-14 16:07
Publish the Manuscript Online
2016-11-18 15:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK
Manuscript Source Invited Manuscript
All Author List Ya-Jing Feng, Yong-Yu Li, Xu-Hong Lin, Kun Li and Ming-Hua Cao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (to Feng YJ) 81400581
National Natural Science Foundation of China (to Li YY) 81270477
Corresponding Author Yong-Yu Li, MD, Department of Pathophysiology, Tongji University School of Medicine, 1239 Siping Road, Shanghai 200092, China. liyongyu@tongji.edu.cn
Key Words Inflammatory bowel disease; Endogenous cannabinoid system; p38MAPK; Experimental colitis; Claudin-1
Core Tip Inflammatory bowel disease demands more effective therapies, and cannabinoids are beneficial in alleviating inflammation in some diseases. In this study, we reported the anti-inflammatory effect and protective role of WIN55-212-2, an agonist of cannabinoid receptors, on the mice with dextran sulfate sodium-induced experimental colitis, and revealed that this agent exerts its action at least partially by inhibiting p38 mitogen-activated protein kinase.
Publish Date 2016-11-18 15:13
Citation Feng YJ, Li YY, Lin XH, Li K, Cao MH. Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK. World J Gastroenterol 2016; 22(43): 9515-9524
URL http://www.wjgnet.com/1007-9327/full/v22/i43/9515.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i43.9515
Full Article (PDF) WJG-22-9515.pdf
Full Article (Word) WJG-22-9515.doc
Manuscript File 27964-Review.doc
Answering Reviewers 27964-Answering reviewers.pdf
Audio Core Tip 27964-Audio core tip.mp3
Biostatistics Review Certificate 27964-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 27964-Conflict-of-interest statement.pdf
Copyright License Agreement 27964-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 27964-Grant application forms.pdf
Institutional Animal Care and Use Committee Approval Form or Document 27964-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 27964-Institutional review board statement.pdf
Peer-review Report 27964-Peer-review(s).pdf
Scientific Misconduct Check 27964-Scientific research process.pdf
Scientific Editor Work List 27964-Scientific editor work list.pdf