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12/13/2016 12:40:00 AM | Browse: 926 | Download: 1742
Publication Name World Journal of Gastroenterology
Manuscript ID 27974
Country United States
Received
2016-06-23 08:25
Peer-Review Started
2016-06-24 13:33
To Make the First Decision
2016-08-29 09:18
Return for Revision
2016-08-29 10:20
Revised
2016-09-27 10:56
Second Decision
2016-10-18 20:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-10-27 17:16
Articles in Press
2016-10-27 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-21 18:16
Publish the Manuscript Online
2016-12-13 00:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Genotype specific peripheral lipid profile changes with hepatitis C therapy
Manuscript Source Invited Manuscript
All Author List Mark R Pedersen, Amit Patel, David Backstedt, Myunghan Choi and Anil B Seetharam
Funding Agency and Grant Number
Corresponding Author Anil B Seetharam, MD, Banner Transplant and Advanced Liver Disease Center, University of Arizona College of Medicine, 1300 N. 12th Street Suite 404, Phoenix, AZ 85006, United States. anil.seetharam@bannerhealth.com
Key Words Hepatitis C genotypes; Lipids; Metabolic syndrome
Core Tip Different genotypes of the hepatitis C virus (HCV) are associated with differing levels of hepatic steatosis, with genotype 3 (GT3) having the strongest direct association. In this investigation, change in peripheral lipid panels during direct-acting antiviral therapy were assessed in a large HCV treatment cohort with respect to genotype. Total cholesterol in patients with GT3 increased significantly during treatment compared to other genotypes. Associated steatosis and differing lipid kinetics may influence response rates to direct acting therapy and may also influence genotype specific risks of hepatic and systemic complications.
Publish Date 2016-12-13 00:40
Citation Pedersen MR, Patel A, Backstedt D, Choi M, Seetharam AB. Genotype specific peripheral lipid profile changes with hepatitis C therapy. World J Gastroenterol 2016; 22(46): 10226-10231
URL http://www.wjgnet.com/1007-9327/full/v22/i46/10226.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i46.10226
Full Article (PDF) WJG-22-10226.pdf
Full Article (Word) WJG-22-10226.doc
Manuscript File 27974-Review.docx
Answering Reviewers 27974-Answering reviewers.pdf
Audio Core Tip 27974-Audio core tip.mp3
Biostatistics Review Certificate 27974-Biostatistics statement.pdf
Clinical Trial Registration Statement DeclarationOf_HelsinkiConformation_Statement_20160623054907.docx
Conflict-of-Interest Disclosure Form 27974-Conflict-of-interest statement.pdf
Copyright License Agreement 27974-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160623054915.docx
Institutional Animal Care and Use Committee Approval Form or Document Institutional_Animal_Care_and_Use_Committee_Statement_20160623054923.docx
Institutional Review Board Approval Form or Document 27974-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20160623054852.docx
Peer-review Report 27974-Peer-review(s).pdf
Scientific Misconduct Check 27974-Scientific misconduct check.pdf
Scientific Editor Work List 27974-Scientific editor work list.pdf