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10/26/2016 5:33:00 PM | Browse: 1035 | Download: 2024
Publication Name World Journal of Gastroenterology
Manuscript ID 28005
Country China
Received
2016-06-24 08:49
Peer-Review Started
2016-06-24 15:40
To Make the First Decision
2016-08-08 09:08
Return for Revision
2016-08-08 10:52
Revised
2016-08-15 22:58
Second Decision
2016-08-23 17:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-08-30 16:56
Articles in Press
2016-08-30 16:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-09-02 03:33
Typeset the Manuscript
2016-10-16 10:40
Publish the Manuscript Online
2016-10-26 17:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Fecal microbiota in pouchitis and ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Kai-Yu Li, Jian-Lin Wang, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang and Gang Liu
Funding Agency and Grant Number
Funding Agency Grant Number
Academician Jie-Shou Li Intestinal Barrier Research Fundation LJS_201008
Corresponding Author Gang Liu, MD, PhD, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China. landmark1503@sina.com
Key Words Pouchitis; Intestinal flora; Ulcerative colitis; Disease activity index; Ileal pouch-anal anastomosis
Core Tip Dysbiosis in pouchitis might be similar to that observed in ulcerative colitis (UC). This study aimed to determine the altered microflora in patients with UC and pouchitis, and to investigate the relationship between them. We demonstrated the reduced biodiversity of the fecal microbiota in UC and pouchitis patients. The altered composition of the intestinal microbiota in UC and pouchitis included decreased numbers of two bacteria commonly observed in UC, and higher levels of Clostridium perfringens in both UC and pouchitis. The increase of this bacterium in feces suggested that it plays a role in exacerbating UC and pouchitis.
Publish Date 2016-10-26 17:34
Citation Li KY, Wang JL, Wei JP, Gao SY, Zhang YY, Wang LT, Liu G. Fecal microbiota in pouchitis and ulcerative colitis. World J Gastroenterol 2016; 22(40): 8929-8939
URL http://www.wjgnet.com/1007-9327/full/v22/i40/8929.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i40.8929
Full Article (PDF) WJG-22-8929.pdf
Full Article (Word) WJG-22-8929.doc
Manuscript File 28005-Review.docx
Answering Reviewers 28005-Answering reviewers.pdf
Audio Core Tip 28005-Audio core tip.mp3
Biostatistics Review Certificate 28005-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28005-Conflict-of-interest statement.pdf
Copyright License Agreement 28005-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 28005-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160624073114.docx
Institutional Review Board Approval Form or Document 28005-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28005-Language certificate.pdf
Peer-review Report 28005-Peer-review(s).pdf
Scientific Misconduct Check 28005-Scientific misconduct check.pdf
Scientific Editor Work List 28005-Scientific editor work list.pdf