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11/26/2016 6:56:00 PM | Browse: 1101 | Download: 1344
Publication Name World Journal of Gastroenterology
Manuscript ID 28052
Country South Korea
Received
2016-06-29 16:39
Peer-Review Started
2016-06-30 10:10
To Make the First Decision
2016-08-08 13:34
Return for Revision
2016-08-12 11:05
Revised
2016-08-26 16:49
Second Decision
2016-09-21 15:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-28 17:40
Articles in Press
2016-09-28 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-10 18:27
Publish the Manuscript Online
2016-11-26 18:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Clinical features of HBsAg seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study
Manuscript Source Invited Manuscript
All Author List Young Min Park and Seong Gyu Lee
Funding Agency and Grant Number
Corresponding Author Young Min Park, MD, PhD, Hepatology Center, Department of Internal Medicine and Biomedical Research Center, Bundang Jesaeng General Hospital, 20, Seohyeon-ro 180 beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do 13589, South Korea. ymp1@outlook.com
Key Words Hepatocellular carcinoma; Hepatitis B virus; Hepatitis B Surface antigen; HBsAg; Seroconversion; Hepatitis B e antigen; HBeAg; Liver cirrhosis
Core Tip In South Korea, where most hepatitis B virus carriers are infected with genotype C, hepatitis B surface antigen (HBsAg) seroclearance rate is 4.7%, and the incidence of hepatocellular carcinoma (HCC) after HBsAg loss is 4.8%. In patients with HBsAg seroclearance, the percentages of asymptomatic liver cirrhosis (LC) and HCC are 31% and 7.8% at enrollment, respectively. A signal-to-cutoff ratio of the qualitative HBsAg level of less than 1000 and its sequential decrease are worth noting as predictive markers of HBsAg loss. HCC surveillance should be continued after HBsAg seroclearance, particularly in patients with LC.
Publish Date 2016-11-26 18:57
Citation Park YM, Lee SG. Clinical features of HBsAg seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study. World J Gastroenterol 2016; 22(44): 9836-9843
URL http://www.wjgnet.com/1007-9327/full/v22/i44/9836.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i44.9836
Full Article (PDF) WJG-22-9836.pdf
Full Article (Word) WJG-22-9836.doc
Manuscript File 28052-Review.docx
Answering Reviewers 28052-Answering reviewers.pdf
Audio Core Tip 28052-Audio core tip.mp3
Biostatistics Review Certificate 28052-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28052-Conflict-of-interest statement.pdf
Copyright License Agreement 28052-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160628230214.pdf
Institutional Review Board Approval Form or Document 28052-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28052-Language certificate.pdf
Peer-review Report 28052-Peer-review(s).pdf
Scientific Misconduct Check 28052-Scientific misconduct check.pdf
Scientific Editor Work List 28052-Scientific editor work list.pdf