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11/13/2016 8:17:00 PM | Browse: 1026 | Download: 1440
Publication Name World Journal of Clinical Cases
Manuscript ID 28139
Country Japan
2016-06-28 09:10
Peer-Review Started
2016-06-29 10:52
To Make the First Decision
2016-08-04 16:14
Return for Revision
2016-08-05 10:19
2016-08-06 07:14
Second Decision
2016-08-19 09:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-08-29 11:52
Articles in Press
2016-08-29 11:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-07 19:23
Publish the Manuscript Online
2016-11-13 20:17
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Case of severe alcoholic hepatitis treated with granulocytapheresis
Manuscript Source Invited Manuscript
All Author List Yukari Watanabe, Kenya Kamimura, Tomohiro Iwasaki, Hiroyuki Abe, Shunsaku Takahashi, Ken-ichi Mizuno, Manabu Takeuchi, Atsushi Eino, Ichiei Narita and Shuji Terai
Funding Agency and Grant Number
Corresponding Author Kenya Kamimura, MD, PhD, Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachido-ri, Chuo-ku, Niigata 951-8510, Japan. kenya-k@med.niigata-u.ac.jp
Key Words Apheresis; Hepatitis; Alcoholic; Alcoholic hepatitis; Case reports
Core Tip Severe alcoholic hepatitis (AH) has a high mortality, and it is associated with encephalopathy, acute renal failure, sepsis, gastrointestinal bleeding, and endotoxemia. Corticosteroids (CS) have shown efficacy in patients with AH by inhibiting the production of cytokines. On the other hand, the use of a CS is not always appropriate during the initial stage when the patient is complicated with the infection, gastrointestinal bleeding, etc. which can be progressed by CS. For these cases, granulocytapheresis (GCAP) is expected to significantly improve the prognosis of those with severe AH, as the granulocyte and monocyte apheresis device inhibits liver injury caused by activated neutrophils. We presented here the case successfully treated with GCAP without using CS because of severe infectious status.
Publish Date 2016-11-13 20:17
Citation Watanabe Y, Kamimura K, Iwasaki T, Abe H, Takahashi S, Mizuno K, Takeuchi M, Eino A, Narita I, Terai S. Case of severe alcoholic hepatitis treated with granulocytapheresis. World J Clin Cases 2016; 4(11): 369-374
URL http://www.wjgnet.com/2307-8960/full/v4/i11/369.htm
DOI http://dx.doi.org/10.12998/wjcc.v4.i11.369
Full Article (PDF) WJCC-4-369.pdf
Full Article (Word) WJCC-4-369.doc
Manuscript File 28139-Review.docx
Answering Reviewers 28139-Answering reviewers.pdf
Audio Core Tip 28139-Audio core tip.wma
Conflict-of-Interest Disclosure Form 28139-Conflict-of-interest statement.pdf
Copyright License Agreement 28139-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 28139-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28139-Language certificate.pdf
Supplementary Material Supplementary_Material_20160627145114.pdf
Peer-review Report 28139-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 28139-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 28139-Scientific misconduct check.pdf
Scientific Editor Work List 28139-Scientific editor work list.pdf