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12/9/2016 9:12:00 AM | Browse: 785 | Download: 1114
Publication Name World Journal of Diabetes
Manuscript ID 28279
Country Nigeria
Received
2016-06-29 11:39
Peer-Review Started
2016-07-01 13:46
To Make the First Decision
2016-09-05 09:06
Return for Revision
2016-09-05 15:50
Revised
2016-09-16 05:44
Second Decision
2016-09-28 11:25
Accepted by Journal Editor-in-Chief
2016-09-29 11:11
Accepted by Company Editor-in-Chief
2016-10-18 16:32
Articles in Press
2016-10-18 16:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-30 17:13
Publish the Manuscript Online
2016-12-09 09:12
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemical Research Methods
Manuscript Type Basic Study
Article Title Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants
Manuscript Source Unsolicited Manuscript
All Author List Stanley Irobekhian Reuben Okoduwa, Ismaila A Umar, Dorcas B James, Hajara M Inuwa and James D Habila
Funding Agency and Grant Number
Corresponding Author Stanley Irobekhian Reuben Okoduwa, Researcher, Directorate of Research and Development, Nigerian Institute of Leather and Science Technology, P.M.B. 1034, Zaria 810004, Nigeria. siroplc@gmail.com
Key Words Extraction techniques; Microwave-assisted-extraction; Maceration; Phytoconstituents; Medicinal plants; Soxhlet; Anti-diabetes
Core Tip Extraction of active phytoconstituents from medicinal plants rely mostly on the use of appropriate extraction method. Different extraction techniques affect the yield and biological activity of phytocomponents. In this study, we observed that microwave assisted extraction produces significantly higher overall extract yield as well as in phenolic, saponin and tannin content. Cold maceration and soxhlet extraction produced higher flavonoid and alkaloid yield respectively. Maceration extracts exhibited significantly better hypoglycemic activities in diabetic rats compared to extracts from soxhlet and microwave assisted extraction. This study reveals that the choice of extraction protocol should depend primarily on the purpose of interest.
Publish Date 2016-12-09 09:12
Citation Okoduwa SIR, Umar IA, James DB, Inuwa HM, Habila JD. Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants. World J Diabetes 2016; 7(20): 605-614
URL http://www.wjgnet.com/1948-9358/full/v7/i20/605.htm
DOI http://dx.doi.org/10.4239/wjd.v7.i20.605
Full Article (PDF) WJD-7-605.pdf
Full Article (Word) WJD-7-605.doc
Manuscript File 28279-Review.doc
Answering Reviewers 28279-Answering reviewers.pdf
Audio Core Tip 28279-Audio core tip.mp3
Biostatistics Review Certificate 28279-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28279-Conflict-of-interest statement.pdf
Copyright License Agreement 28279-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 28279-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 28279-Institutional review board statement.pdf
Peer-review Report 28279-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 28279-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 28279-Scientific misconduct check.pdf
Scientific Editor Work List 28279-Scientific editor work list.pdf