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11/18/2016 3:13:00 PM | Browse: 1037 | Download: 2090
Publication Name World Journal of Gastroenterology
Manuscript ID 28307
Country China
Received
2016-07-11 09:24
Peer-Review Started
2016-07-13 15:52
To Make the First Decision
2016-08-22 14:28
Return for Revision
2016-08-24 18:35
Revised
2016-09-18 22:17
Second Decision
2016-09-30 10:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-10-10 17:16
Articles in Press
2016-10-10 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-10-16 12:33
Typeset the Manuscript
2016-11-12 13:44
Publish the Manuscript Online
2016-11-18 15:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Allergy
Manuscript Type Retrospective Study
Article Title Ceruloplasmin, a reliable marker of fibrosis in chronic hepatitis B virus patients with normal or minimally raised alanine aminotransferase
Manuscript Source Invited Manuscript
All Author List Da-Wu Zeng, Jing Dong, Jia-Ji Jiang, Yue-Yong Zhu and Yu-Rui Liu
Funding Agency and Grant Number
Funding Agency Grant Number
Youth Foundation of the Health and Family Planning Commission of Fujian Province 2014-1-55
Corresponding Author Yue-Yong Zhu, MD, Liver Center, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. ezhu066@sina.com
Key Words Chronic hepatitis B; Liver biopsy; Fibrosis; Cirrhosis; Ceruloplasmin
Core Tip To date, few non-invasive approaches have been developed to evaluate liver fibrosis and no studies have proposed measuring ceruloplasmin (CP) levels for predicting liver fibrosis in chronic hepatitis B (CHB) virus patients with normal or minimally raised alanine aminotransferase (ALT). This study showed CP was independently and negatively associated with liver fibrosis. Furthermore, a simple and accurate CG model was developed to predict significant liver fibrosis and cirrhosis in CHB patients with normal or mildly elevated ALT. This model may be a valuable tool to replace liver biopsy in this category of hepatitis B virus-infected patients.
Publish Date 2016-11-18 15:13
Citation Zeng DW, Dong J, Jiang JJ, Zhu YY, Liu YR. Ceruloplasmin, a reliable marker of fibrosis in chronic hepatitis B virus patients with normal or minimally raised alanine aminotransferase. World J Gastroenterol 2016; 22(43): 9586-9594
URL http://www.wjgnet.com/1007-9327/full/v22/i43/9586.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i43.9586
Full Article (PDF) WJG-22-9586.pdf
Full Article (Word) WJG-22-9586.doc
Manuscript File 28307-Review.doc
Answering Reviewers 28307-Answering reviewers.pdf
Audio Core Tip 28307-Audio core tip.mp3
Biostatistics Review Certificate 28307-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28307-Conflict-of-interest statement.pdf
Copyright License Agreement 28307-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 28307-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160710120451.docx
Institutional Review Board Approval Form or Document 28307-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 28307-Language certificate.pdf
Peer-review Report 28307-Peer-review(s).pdf
Scientific Misconduct Check 28307-Scientific misconduct check.pdf
Scientific Editor Work List 28307-Scientific editor work list.pdf