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12/6/2016 5:24:00 PM | Browse: 1078 | Download: 1791
Publication Name World Journal of Gastroenterology
Manuscript ID 29199
Country China
Received
2016-08-02 09:47
Peer-Review Started
2016-08-02 10:11
To Make the First Decision
2016-08-19 15:12
Return for Revision
2016-08-23 10:12
Revised
2016-09-07 00:00
Second Decision
2016-09-21 15:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-28 18:06
Articles in Press
2016-09-28 18:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-10-26 03:54
Typeset the Manuscript
2016-11-16 20:32
Publish the Manuscript Online
2016-12-06 17:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Smoc2 potentiates proliferation of hepatocellular carcinoma cells via promotion of cell cycle progression
Manuscript Source Unsolicited Manuscript
All Author List Jing-Ran Su, Jing-Hua Kuai and Yan-Qing Li
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81330012
Corresponding Author Yan-Qing Li, MD, PhD, Department of Gastroenterology, Laboratory of Translational Gastroenterology, Shandong University, Qilu Hospital, 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China. liyanqing@sdu.edu.cn
Key Words Smoc2; Hepatocellular carcinoma; Cell cycle; Proliferation
Core Tip In our study, we confirmed that Smoc2 was up-regulated in hepatocellular carcinoma (HCC) tissues and played an important role in regulating liver cancer cell proliferation. Besides, we verified that Smoc2 participated in promoting HCC cell proliferation mainly through regulation of cell cycle progression. We have not investigated the promotive role of Smoc2 in regulating cell proliferation, whether it is through cell cycle regulation only or involves regulation of cell apoptosis as well. Moreover, the exact mechanism of how Smoc2 regulates cell cycle remains unclear. The core contents of our study included Smoc2 promotion of HCC cell proliferation via accelerating cell cycle progression.
Publish Date 2016-12-06 17:24
Citation Su JR, Kuai JH, Li YQ. Smoc2 potentiates proliferation of hepatocellular carcinoma cells via promotion of cell cycle progression. World J Gastroenterol 2016; 22(45): 10053-10063
URL http://www.wjgnet.com/1007-9327/full/v22/i45/10053.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i45.10053
Full Article (PDF) WJG-22-10053.pdf
Full Article (Word) WJG-22-10053.doc
Manuscript File 29199-Review.doc
Answering Reviewers 29199-Answering reviewers.pdf
Audio Core Tip 29199-Audio core tip.mp3
Biostatistics Review Certificate 29199-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 29199-Conflict-of-interest statement.pdf
Copyright License Agreement 29199-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 29199-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160801194650.pdf
Institutional Review Board Approval Form or Document 29199-Instituional review board statement.pdf
Peer-review Report 29199-Peer-review(s).pdf
Scientific Editor Work List 29199-Scientific editor work list.pdf