Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	2954
Country	United States

Received	2013-03-28 09:33
Peer-Review Started	2013-03-29 10:08
To Make the First Decision	2013-05-02 10:35
Return for Revision	2013-05-17 16:00
Revised	2013-05-30 04:04
Second Decision	2013-07-01 12:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-07-01 23:44
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-11 19:00
Publish the Manuscript Online	2013-11-08 10:03

ISSN	2219-2808 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Autobiography
Article Title	Tramadol use in pediatric sickle cell disease patients with vaso-occlusive crisis
Manuscript Source	Invited Manuscript
All Author List	Mary P Borgerding, Randall K Absher and Tsz-Yin So
Funding Agency and Grant Number
Corresponding Author	Tsz-Yin So, PhD, BCPS, Department of Pharmacy, Moses H. Cone Memorial Hospital, 1200 N. Elm St., Greensboro, NC 27401, United States. jeremy.so@conehealth.com
Key Words	Pediatrics; Sickle cell; Tramadol; Morphine; Vaso-occlusive crisis
Core Tip	A small clinical study has shown that balanced analgesia using intravenous morphine, intravenous ketorolac, and intravenous tramadol followed by erythrocytapheresis was effective, as shown by pain relief and significant improvement in mood and sleep, in seven sickle cell disease patients aged three to twenty-eight years who presented with vaso-occlusive crisis. The objective of this study is to evaluate whether the addition of scheduled oral tramadol to intravenous morphine plus intravenous ketorolac provides adequate pain relief, and reduces morphine requirements, adverse effects, length of patient-controlled analgesia therapy, and length of hospital stay.
Publish Date	2013-11-08 10:03
Citation	Borgerding MP, Absher RK, So TY. Tramadol use in pediatric sickle cell disease patients with vaso-occlusive crisis. World J Clin Pediatr 2013; 2(4): 65-69
URL	http://www.wjgnet.com/2219-2808/full/v2/i4/65.htm
DOI	http://dx.doi.org/10.5409/wjcp.v2.i4.65

Full Article (PDF)	WJCP-2-65.pdf
Manuscript File	2954-Review.doc
Answering Reviewers	2954-Answering reviewers.pdf
Copyright License Agreement	2954-Copyright assignment.pdf
Peer-review Report	2954-Peer review(s).pdf
Scientific Editor Work List	2954-Scientific editor work list.doc