Publication Name	World Journal of Gastroenterology
Manuscript ID	2963
Country	China

Received	2013-03-29 08:31
Peer-Review Started	2013-03-29 10:46
To Make the First Decision	2013-05-02 10:35
Return for Revision	2013-05-17 16:53
Revised	2013-06-21 10:25
Second Decision	2013-07-01 17:34
Accepted by Journal Editor-in-Chief	2013-07-01 18:48
Accepted by Company Editor-in-Chief	2013-07-11 13:10
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-24 15:13
Publish the Manuscript Online	2013-08-06 09:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy
Manuscript Source	Invited Manuscript
All Author List	Can-Xia Xu, Xiong Chen, Yan Jia, Ding-Hua Xiao, Hui-Fang Zou, Qin Guo, Fen Wang, Xiao-Yan Wang, Shou-Rong Shen, Ling-Ling Tong, Ke Cao and Xiao-Ming Liu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81172301
Corresponding Author	Can-Xia Xu, MD, Professor, Department of Gastroenterology, Third Xiangya Hospital of Central South University, 138 Tongzipo Street, Changsha 410013, Hunan Province, China. xucanxia2000@hotmail.com
Key Words	Upper gastrointestinal endoscopy; Adverse events; Sedation; Monitoring; Chronic obstructive pulmonary disease
Core Tip	Many patients with chronic obstructive pulmonary disease (COPD) have to undergo upper gastrointestinal (GI) endoscopy because of digestive symptoms. A sedation method specially designed for elderly patients with COPD is urgently needed for use in clinical practice. In this study, we designed a new stepwise sedation method. Eighty-six elderly patients with COPD and 82 elderly patients without COPD scheduled for upper GI endoscopy were randomly assigned stepwise sedation or continuous sedation. The results indicate that the stepwise sedation method is effective and safer than the continuous sedation method for elderly patients with mild/moderate COPD during upper GI endoscopy.
Publish Date	2013-08-06 09:19
Citation	Xu CX, Chen X, Jia Y, Xiao DH, Zou HF, Guo Q, Wang F, Wang XY, Shen SR, Tong LL, Cao K, Liu XM. Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy. World J Gastroenterol 2013; 19(29): 4791-4798
URL	http://www.wjgnet.com/1007-9327/full/v19/i29/4791.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i29.4791

Full Article (PDF)	WJG-19-4791.pdf
Manuscript File	2963-Review.doc
Answering Reviewers	2963-Answering reviewers.doc
Biostatistics Review Certificate	biostatistical review report.jpg
Copyright License Agreement	2963-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethical certificate.jpg
Non-Native Speakers of English Editing Certificate	2963-Language certificate.pdf
Peer-review Report	2963-Peer review(s).pdf
Scientific Editor Work List	2963-Scientific editor work list.doc