| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Hepatic arterial infusion chemotherapy in hepatocellular carcinoma with portal vein tumor thrombosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Do Seon Song, Si Hyun Bae, Myeong Jun Song, Sung Won Lee, Hee Yeon Kim, Young Joon Lee, Jung Suk Oh, Ho Jong Chun, Hae Giu Lee, Jong Young Choi and Seung Kew Yoon |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National R and D Program Grant for Cancer Control from the Ministry of Health, Welfare and Family Affairs, Republic of Korea |
R0620390-1 |
|
| Corresponding Author |
Si Hyun Bae, MD, PhD, Professor, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, #505 Banpo-dong, Seocho-gu, Seoul 137-040, South Korea. baesh@catholic.ac.kr
|
| Key Words |
Hepatocellular carcinoma; Hepatic arterial infusion chemotherapy; Portal vein tumor thrombosis |
| Core Tip |
The aim of this study was to investigate the prognostic factors of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma patients with portal vein tumor thrombosis. The primary findings of this study were as follows: (1) The median survival and time to progression were 7 and 2 mo, respectively; (2) A tumor volume of < 400 cm3 and protein induced by vitamin K absence or antagonist-Ⅱ were independent pre-treatment prognostic factors; (3) Disease control and ≥ 50% tumor marker reduction were significant prognostic factors after the second cycle of hepatic arterial infusion chemotherapy (HAIC); and (4) Objective tumor response, disease control and portal vein tumor thrombosis response were independent post-treatment prognostic factors at the end of the HAIC. |
| Publish Date |
2013-08-06 09:19 |
| Citation |
Song DS, Bae SH, Song MJ, Lee SW, Kim HY, Lee YJ, Oh JS, Chun HJ, Lee HG, Choi JY, Yoon SK. Hepatic arterial infusion chemotherapy in hepatocellular carcinoma with portal vein tumor thrombosis. World J Gastroenterol 2013; 19(29): 4679-4688 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i29/4679.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i29.4679 |
