Publication Name	World Journal of Gastroenterology
Manuscript ID	2992
Country	Germany

Received	2013-03-31 16:14
Peer-Review Started	2013-03-31 21:35
To Make the First Decision	2013-05-02 10:33
Return for Revision	2013-05-17 18:16
Revised	2013-06-08 22:08
Second Decision	2013-07-17 18:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-07-18 13:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-21 19:32
Publish the Manuscript Online	2013-09-09 09:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Biliary phosphatidylcholine and lysophosphatidylcholine profiles in sclerosing cholangitis
Manuscript Source	Unsolicited Manuscript
All Author List	Annika Gauss, Robert Ehehalt, Wolf-Dieter Lehmann, Gerhard Erben, Karl-Heinz Weiss, Yvonne Schaefer, Petra Kloeters-Plachky, Adolf Stiehl, Wolfgang Stremmel, Peter Sauer and Daniel Nils Gotthardt
Funding Agency and Grant Number	Funding Agency Grant Number Deutsche Forschungsgemeinschaft (DFG)
Corresponding Author	Annika Gauss, MD, Gastroenterology and Hepatology Unit, Department of Internal Medicine, University Hospital Heidelberg, INF 410, Heidelberg 69120, Germany. annika.gauss@med.uni-heidelberg.de
Key Words	Primary sclerosing cholangitis; Secondary sclerosing cholangitis; Cholangiocellular carcinoma; Phosphatidylcholine; Lysophosphatidylcholine; Bile; Mass spectrometry
Core Tip	Based on the idea that unfavorable alterations of biliary phospholipids might play a role in the pathogenesis of sclerosing cholangitis, phosphatidylcholine (PC) and lysophosphatidylcholine (LPC) species profiles were analyzed in endoscopically-acquired intrahepatic bile using nano-electrospray ionization tandem mass spectrometry. The examination of specimens from 14 patients with primary sclerosing cholangitis, 10 patients with secondary sclerosing cholangitis, 11 patients with choledocholithiasis/no biliary disease and 6 patients with cholangiocellular carcinoma revealed strikingly similar PC and LPC species patterns, implicating at the most a minor role of biliary phospholipid changes in sclerosing cholangitis.
Publish Date	2013-09-09 09:30
Citation	Gauss A, Ehehalt R, Lehmann WD, Erben G, Weiss KH, Schaefer Y, Kloeters-Plachky P, Stiehl A, Stremmel W, Sauer P, Gotthardt DN. Biliary phosphatidylcholine and lysophosphatidylcholine profiles in sclerosing cholangitis. World J Gastroenterol 2013; 19(33): 5454-5463
URL	http://www.wjgnet.com/1007-9327/full/v19/i33/5454.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i33.5454

Full Article (PDF)	WJG-19-5454.pdf
Manuscript File	2992-Review.doc
Answering Reviewers	2992-Answering reviewers.pdf
Copyright License Agreement	2992-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2992-Language certificate.pdf
Peer-review Report	2992-Peer review(s).pdf
Scientific Editor Work List	2992-Scientific editor work list.doc