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2/27/2017 8:50:00 AM | Browse: 1055 | Download: 1305
Publication Name World Journal of Hepatology
Manuscript ID 30306
Country Brazil
Received
2016-09-26 09:06
Peer-Review Started
2016-09-27 07:59
To Make the First Decision
2016-11-22 16:39
Return for Revision
2016-11-23 16:28
Revised
2016-12-15 09:19
Second Decision
2017-01-05 17:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-02-13 13:45
Articles in Press
2017-02-13 13:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-22 20:33
Publish the Manuscript Online
2017-02-27 08:50
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Fibrosis assessment using FibroMeter combined to first generation tests in hepatitis C
Manuscript Source Invited Manuscript
All Author List Maria Chiara Chindamo, Jerome Boursier, Ronir Raggio Luiz, Isabelle Fouchard-Hubert, Vera Lúcia Nunes Pannain, João Marcelo de Araújo Neto, Henrique Sérgio Moraes Coelho, Renata de Mello Perez, Paul Calès and Cristiane Alves Villela-Nogueira
Funding Agency and Grant Number
Corresponding Author Maria Chiara Chindamo, MD, PhD, Adjunt Professor, Department of Internal Medicine, Federal University of Rio de Janeiro, Avenida Lúcio Costa 3602, apto 1304 bloco 2, Barra da Tijuca, Rio de Janeiro 22630-010, Brazil. mchiara@terra.com.br
Key Words Chronic hepatitis C; Fibrosis; Liver biopsy; Non-invasive methods; FibroMeterVirus3G; Combination algorithms
Core Tip Liver fibrosis assessment still poses a challenge when prioritizing hepatitis C treatment due to logistical and financial barriers in the use of direct acting antiviral drugs. We introduced a new stepwise combination of first generation fibrosis tests - aminotransferase-to-platelet ratio index (APRI) and Forns-followed by FibroMeterVirus3G whenever results remained unclassified after first generation tests to identify significant fib-rosis. This combination presented similar accuracy to FibroMeterVirus3G used as the only test, reduced APRI and Forns grey zone, and spared FibroMeterVirus3G require-ment in 50% of cases. This approach represents a lower-cost alternative to assess fibrosis, with no need for liver biopsy.
Publish Date 2017-02-27 08:50
Citation Chindamo MC, Boursier J, Luiz RR, Fouchard-Hubert I, Pannain VLN, de Araújo Neto JM, Coelho HSM, de Mello Perez R, Calès P, Villela-Nogueira CA. Fibrosis assessment using FibroMeter combined to first generation tests in hepatitis C. World J Hepatol 2017; 9(6): 310-317
URL http://www.wjgnet.com/1948-5182/full/v9/i6/310.htm
DOI http://dx.doi.org/10.4254/wjh.v9.i6.310
Full Article (PDF) WJH-9-310.pdf
Full Article (Word) WJH-9-310.doc
Manuscript File 30306-Review.docx
Answering Reviewers 30306-Answering reviewers.pdf
Audio Core Tip 30306-Audio core tip.m4a
Biostatistics Review Certificate 30306-Biostatistics statement.pdf
Clinical Trial Registration Statement DeclarationOf_HelsinkiConformation_Statement_20160925224348.bmp
Conflict-of-Interest Disclosure Form 30306-Conflict-of-interest statement.pdf
Copyright License Agreement 30306-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160925223451.pdf
Institutional Review Board Approval Form or Document 30306-Institutional review board statement.pdf
Peer-review Report 30306-Peer-review(s).pdf
Scientific Misconduct Check 30306-Scientific misconduct check.pdf
Scientific Editor Work List 30306-Scientific editor work list.pdf