| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Anti-inflammatory intestinal activity of Combretum duarteanum Cambess. in trinitrobenzene sulfonic acid colitis model
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gedson Rodrigues de Morais Lima, Flavia Danniele Frota Machado, Larissa Lucena Périco, Felipe Meira de Faria, Anderson Luiz-Ferreira, Alba Regina Monteiro Souza Brito, Cláudia Helena Pellizzon, Clélia Akiko Hiruma-Lima, Josean Fechine Tavares, José Maria Barbosa Filho and Leônia Maria Batista |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Leônia Maria Batista, PhD, Departamento de Ciências Farmacêuticas, Centro de Ciências da Saúde, Laboratório de Farmacologia do Trato Gastrintestinal, Universidade Federal da Paraíba (UFPB), Cidade Universitária, s/n - Castelo Branco, João Pessoa, Paraíba, CEP 58051-970, Brazil. leoniab@uol.com.br |
| Key Words |
Combretum duarteanum; Medicinal plants; Combretaceae; Inflammatory bowel disease; Anti-inflammatory intestinal activity |
| Core Tip |
Inflammatory bowel diseases are chronic inflammatory disorders that include Crohn’s disease and ulcerative colitis (UC). Genetic, immunologic and environmental factors are postulated as possible etiologic agents. Their conventional treatment is centered in reducing inflammation and abnormal symptom relief. A variety of herbal medicines have been demonstrated to produce promising results in the treatment of those diseases. Combretum duarteanum is a species popularly used in folk medicine to treat inflammation. Thus, the present study was designed to evaluate the intestinal anti-inflammatory effect in an UC rat model, contributing to the safe use and collaborating with the scientific knowledge of natural products. |
| Publish Date |
2017-02-26 18:20 |
| Citation |
de Morais Lima GR, Machado FDF, Périco LL, de Faria FM, Luiz-Ferreira A, Souza Brito ARM, Pellizzon CH, Hiruma-Lima CA, Tavares JF, Barbosa Filho JM, Batista LM. Anti-inflammatory intestinal activity of Combretum duarteanum Cambess. in trinitrobenzene sulfonic acid colitis model. World J Gastroenterol 2017; 23(8): 1353-1366 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i8/1353.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i8.1353 |
