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Publication Name World Journal of Gastroenterology
Manuscript ID 30400
Country China
Received
2016-10-07 16:36
Peer-Review Started
2016-10-08 18:40
To Make the First Decision
2016-12-19 11:29
Return for Revision
2016-12-20 10:42
Revised
2017-01-13 09:58
Second Decision
2017-01-16 13:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-17 16:57
Articles in Press
2017-01-17 16:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-02-04 11:51
Typeset the Manuscript
2017-02-16 20:04
Publish the Manuscript Online
2017-02-26 18:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Different phenotypes of monocytes in patients with new-onset mild acute pancreatitis
Manuscript Source Invited Manuscript
All Author List Man-Li Zhang, Yan-Fang Jiang, Xin-Rui Wang, Li-Li Ding, Hong-Juan Wang, Qing-Qing Meng and Pu-Jun Gao
Funding Agency and Grant Number
Corresponding Author Pu-Jun Gao, MD, PhD, Department of Hepatology, The First Hospital of Jilin University, 71 Xinmin Street, Changchun 130021, Jilin Province, China. pujun-gao@163.com
Key Words Mild acute pancreatitis; Monocyte; Cytokine; Acute physiology and chronic health evaluation II score; C-reactive protein
Core Tip This is the first study on the numbers of different phenotypes of peripheral blood monocytes in patients with new-onset mild acute pancreatitis (MAP). Increased numbers of CD14+CD163- and CD14+CD163-MAC387+ M1 monocytes were positively correlated with the levels of plasma C-reactive protein (CRP), which suggest that pro-inflammatory monocytes may participate in the pathogenesis of MAP. The increased numbers of CD14+CD163+CD115+ M2 monocytes were positively correlated with the plasma CRP levels and the acute physiology and chronic health evaluation II scores, suggesting that the numbers of CD14+CD163+CD115+ monocytes may be a valuable biomarker for evaluating the severity of MAP. Our findings may provide new insights into the pathogenic process and immunoregulation of MAP.
Publish Date 2017-02-26 18:20
Citation Zhang ML, Jiang YF, Wang XR, Ding LL, Wang HJ, Meng QQ, Gao PJ. Different phenotypes of monocytes in patients with new-onset mild acute pancreatitis. World J Gastroenterol 2017; 23(8): 1477-1488
URL http://www.wjgnet.com/1007-9327/full/v23/i8/1477.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i8.1477
Full Article (PDF) WJG-23-1477.pdf
Full Article (Word) WJG-23-1477.doc
Manuscript File 30400-Review.doc
Answering Reviewers 30400-Answering reviewers.pdf
Audio Core Tip 30400-Audio core tip.mp3
Biostatistics Review Certificate 30400-Biostatisticsstatement.pdf
Conflict-of-Interest Disclosure Form 30400-Conflict-of-intereststatement.pdf
Copyright License Agreement 30400-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160930095259.pdf
Institutional Review Board Approval Form or Document 30400-Institutional review boardstatement.pdf
Non-Native Speakers of English Editing Certificate 30400-Language certificate.pdf
Peer-review Report 30400-Peer-review(s).pdf
Scientific Misconduct Check 30400-Scientific misconduct check.pdf
Scientific Editor Work List 30400-Scientific editor work list.pdf