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5/6/2017 8:30:21 PM | Browse: 800 | Download: 2175
Publication Name World Journal of Gastroenterology
Manuscript ID 30672
Country China
Received
2016-10-13 09:21
Peer-Review Started
2016-10-14 08:25
To Make the First Decision
2016-12-28 17:26
Return for Revision
2016-12-29 10:32
Revised
2017-01-16 21:47
Second Decision
2017-02-15 19:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-02-17 10:11
Articles in Press
2017-02-17 10:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-03-29 16:41
Typeset the Manuscript
2017-04-24 14:26
Publish the Manuscript Online
2017-05-06 20:30
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Study
Article Title Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis
Manuscript Source Unsolicited Manuscript
All Author List Shao-Hua Li, Qiao-Xuan Wang, Zhong-Yuan Yang, Wu Jiang, Cong Li, Peng Sun, Wei Wei, Ming Shi and Rong-Ping Guo
Funding Agency and Grant Number
Corresponding Author Rong-Ping Guo, MD, Department of Hepatobiliary Surgery, Cancer Center of Sun Yat-Sen University, 651 Dongfeng East Road, Guangzhou 510275, Guangdong Province, China. guorp@sysucc.org.cn
Key Words Hepatocellular carcinoma; Portal/hepatic vein tumor thrombosis; Neutrophil-to-lymphocyte ratio; Prognosis
Core Tip The systemic inflammatory response generated by tumors has been shown to cause the upregulation of cytokines and inflammatory mediators, leading to the promotion of angiogenesis and DNA damage and the inhibition of apoptosis. The presence of a systemic inflammatory response can be detected by the elevation of the neutrophil-to-lymphocyte ratio (NLR), which has been shown to be associated with poorer prognosis in patients with various types of malignant tumors. Our findings confirm that the NLR can be used as a potential prognostic predictor for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis after resection. The results of the present study may help identify a new serum marker for predicting the post-operation survival of these patients.
Publish Date 2017-05-06 20:30
Citation Li SH, Wang QX, Yang ZY, Jiang W, Li C, Sun P, Wei W, Shi M, Guo RP. Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis. World J Gastroenterol 2017; 23(17): 3122-3132
URL http://www.wjgnet.com/1007-9327/full/v23/i17/3122.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i17.3122
Full Article (PDF) WJG-23-3122.pdf
Full Article (Word) WJG-23-3122.doc
Manuscript File 30672-Review.docx
Answering Reviewers 30672-Answering reviewers.pdf
Audio Core Tip 30672-Audio core tip.mp3
Biostatistics Review Certificate 30672-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 30672-Conflict-of-interest statement.pdf
Copyright License Agreement 30672-Copyright assignment.PDF
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20161013002717.docx
Institutional Review Board Approval Form or Document 30672-Institutional review board statement.pdf
Peer-review Report 30672-Peer-review(s).pdf
Scientific Misconduct Check 30672-Scientific misconduct check.pdf
Scientific Editor Work List 30672-Scientific editor work list.pdf