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2/26/2017 6:20:00 PM | Browse: 959 | Download: 1135
Publication Name World Journal of Gastroenterology
Manuscript ID 30911
Country/Territory Japan
Received
2016-10-23 17:43
Peer-Review Started
2016-10-25 09:03
To Make the First Decision
2016-12-02 08:16
Return for Revision
2016-12-02 11:45
Revised
2016-12-05 22:25
Second Decision
2016-12-16 17:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-12-21 16:26
Articles in Press
2016-12-21 16:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-01-06 17:53
Publish the Manuscript Online
2017-02-26 18:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Hepatitis C infected patients need vitamin D3 supplementation in the era of direct acting antivirals treatment
Manuscript Source Invited Manuscript
All Author List Yasuteru Kondo
Funding Agency and Grant Number
Corresponding Author Yasuteru Kondo, MD, PhD, Chief Director, Department of Hepatology, Sendai Kousei Hospital, 4-15 Hirosemachi, Aoba, Sendai City 980, Miyagi, Japan. yasuteru@ebony.plala.or.jp
Key Words Vitamin D; Hepatitis C virus; Direct acting antivirals; Hepatocarcinogenesis; Immune response
Core Tip Although several mechanisms for the favorable effects of vitamin D3 (VitD3) supplementation were reported, the total effect of VitD3 supplementation remains unclear. Recently, the main treatment of chronic hepatitis C should be direct acting antivirals (DAAs) without pegylated interferon (Peg-IFN). Peg-IFN is a strong immune-modulator. Therefore, an immuno-logical analysis should be carried out to understand the effect of VitD3 after treatment of DAAs without Peg-IFN. The induction of a favorable immune response by adding VitD3 might be able to suppress the hepa-tocarcinogenesis after achieving SVR, especially in children and elderly patients with severe fibrosis lacking sufficient amounts of VitD3.
Publish Date 2017-02-26 18:20
Citation Kondo Y. Hepatitis C infected patients need vitamin D3 supplementation in the era of direct acting antivirals treatment. World J Gastroenterol 2017; 23(8): 1325-1327
URL http://www.wjgnet.com/1007-9327/full/v23/i8/1325.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i8.1325
Full Article (PDF) WJG-23-1325.pdf
Full Article (Word) WJG-23-1325.doc
Manuscript File 30911-Review.docx
Answering Reviewers 30911-Answering reviewers.pdf
Audio Core Tip 30911-Audio core tip.wav
Conflict-of-Interest Disclosure Form 30911-Conflict-of-interest statement.pdf
Copyright License Agreement 30911-Copyright assignment.pdf
Peer-review Report 30911-Peer-review(s).pdf
Scientific Misconduct Check 30911-Scientific misconduct check.pdf
Scientific Editor Work List 30911-Scientific editor work list.pdf