ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon thiswork non-commercially, and license their derivative works ondifferent terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Diabetes recurrence after metabolic surgeries correlates with re-impaired insulin sensitivity rather than beta-cell function
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Teng Liu, Ming-Wei Zhong, Yi Liu, Dong Sun, Meng Wei, Xin Huang, Yu-Gang Cheng, Qun-Zheng Wu, Dong Wu, Xiao-Qian Zhang, Ke-Xin Wang, San-Yuan Hu and Shao-Zhuang Liu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81300286 |
National Natural Science Foundation of China |
81471019 |
Foundation for Outstanding Young Scientist in Shandong Province |
BS2013YY031 |
Science and Technology Development Program of Shandong Province |
2014GGE27485 |
Specialized Research Fund for the Doctoral Program of Higher Education of China |
20130131120069 |
|
Corresponding Author |
Shao-Zhuang Liu, MD, PhD, Department of General Surgery, Qilu Hospital of Shandong University, No. 107, Wenhua Xi Road, Jinan 250012, Shandong Province, China. liushaozhuang@sdu.edu.cn |
Key Words |
Apoptosis; Diabetes recurrence; Duodenal-jejunal bypass; Pancreatic beta cell; Sleeve gastrectomy |
Core Tip |
To investigate factors causing diabetes recurrence after sleeve gastrectomy (SG) and duodenal-jejunal bypass (DJB), we performed SG and DJB on diabetic rats and high-fat diet was used to induce diabetes recurrence at 4 wk postoperatively. The result showed that diabetes recurrence may correlate with re-impaired insulin sensitivity, but not with alterations of beta-cell function and body weight. |
Publish Date |
2017-05-20 12:26 |
Citation |
Liu T, Zhong MW, Liu Y, Sun D, Wei M, Huang X, Cheng YG, Wu QZ, Wu D, Zhang XQ, Wang KX, Hu SY, Liu SZ. Diabetes recurrence after metabolic surgeries correlates with re-impaired insulin sensitivity rather than beta-cell function. World J Gastroenterol 2017; 23(19): 3468-3479 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i19/3468.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i19.3468 |