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8/7/2017 9:17:02 AM | Browse: 1193 | Download: 1931
Publication Name World Journal of Gastroenterology
Manuscript ID 32942
Country/Territory China
Received
2017-01-30 17:05
Peer-Review Started
2017-02-02 21:40
To Make the First Decision
2017-04-05 17:18
Return for Revision
2017-04-06 09:08
Revised
2017-04-25 02:21
Second Decision
2017-06-27 06:07
Accepted by Journal Editor-in-Chief
2017-06-28 07:38
Accepted by Company Editor-in-Chief
2017-07-04 05:50
Articles in Press
2017-07-04 05:50
Publication Fee Transferred
2017-07-05 05:40
Edit the Manuscript by Language Editor
2017-07-07 13:23
Typeset the Manuscript
2017-07-31 10:31
Publish the Manuscript Online
2017-08-07 09:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title PBX1 attributes as a determinant of connexin 32 downregulation in Helicobacter pylori-related gastric carcinogenesis
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Ming Liu, Can-Xia Xu, Lin-Fang Zhang, Li-Hua Huang, Ting-Zi Hu, Rong Li, Xiu-Juan Xia, Lin-Yong Xu, Ling Luo, Xiao-Xia Jiang and Ming Li
Funding Agency and Grant Number
Funding Agency Grant Number
New Xiangya Talent Project of the Third Xiangya Hospital of Central South University 20150310
Corresponding Author Can-Xia Xu, MD, Department of Gastroenterology, the Third Xiangya Hospital of Central South University, No. 138 Tongzipo Street, Changsha 410013, Hunan Province, China. xucanxia2000@163.com
Key Words Helicobacter pylori; Inflammation-carcinoma chain; Connexin 32; PBX1; Carcinogenesis
Core Tip In this paper, we first report on the increasing tendency of transcriptional factor PBX1 in response to Helicobacter pylori (H. pylori) infection. This is sig­nificant because H. pylori is the predominant factor of gastric carcinoma, and the enhanced PBX1 expression in epithelial cells was first revealed as a marker of H. pylori-associated gastric carcinogenesis. Moreover, PBX1 transcriptionally downregulates the expression of connexin 32, which is vital to epithelial cell-cell communication, indicating an anti-cancer target that prevents the accumulation of PBX1 in the presence of H. pylori infection.
Publish Date 2017-08-07 09:17
Citation Liu XM, Xu CX, Zhang LF, Huang LH, Hu TZ, Li R, Xia XJ, Xu LY, Luo L, Jiang XX, Li M. PBX1 attributes as a determinant of connexin 32 downregulation in Helicobacter pylori-related gastric carcinogenesis. World J Gastroenterol 2017; 23(29): 5345-5355
URL http://www.wjgnet.com/1007-9327/full/v23/i29/5345.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i29.5345
Full Article (PDF) WJG-23-5345.pdf
Full Article (Word) WJG-23-5345.doc
Manuscript File 32942-Review.docx
Answering Reviewers 32942-Answering reviewers.pdf
Audio Core Tip 32942-Audio core tip.mp3
Biostatistics Review Certificate 32942-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 32942-Conflict-of-interest statement.pdf
Copyright License Agreement 32942-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 32942-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 32942-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 32942-Language certificate.pdf
Supplementary Material 32942-Supplementary material.pdf
Peer-review Report 32942-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 32942-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 32942-Scientific misconduct check.pdf
Scientific Editor Work List 32942-Scientific editor work list.pdf