ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, and build upon this work non-commercially, as well as license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Present and future of metastatic colorectal cancer treatment: A review of new candidate targets
|
Manuscript Source |
Invited Manuscript |
All Author List |
Giulia Martini, Teresa Troiani, Claudia Cardone, Pietro Vitiello, Vincenzo Sforza, Davide Ciardiello, Stefania Napolitano, Carminia Maria della Corte, Floriana Morgillo, Antonio Raucci, Antonio Cuomo, Francesco Selvaggi, Fortunato Ciardiello and Erika Martinelli |
Funding Agency and Grant Number |
|
Corresponding Author |
Erika Martinelli, MD, PhD, Assistant Professor, Department of Internal and Experimental Medicine “F. Magrassi e A. Lanzara”, Institute of Medical Oncology, Università degli studi della Campania Luigi Vanvitelli, via Pansini 5, 80131 Naples, Italy. erika.martinelli@unina2.it |
Key Words |
Novel biomarkers; Monoclonal antibodies; Resistance; Mutation; RAS; Target therapy; Metastatic colorectal cancer |
Core Tip |
Colorectal cancer is a heterogeneous disease characterized by several molecular alterations that affect genes implicated in cancer development. The discovery of novel biomarkers, together with a better understand of the complex biology of the disease, is essential to identify patients who will most likely benefit from personalized treatment. |
Publish Date |
2017-07-12 06:45 |
Citation |
Martini G, Troiani T, Cardone C, Vitiello P, Sforza V, Ciardiello D, Napolitano S, Della Corte CM, Morgillo F, Raucci A, Cuomo A, Selvaggi F, Ciardiello F, Martinelli E. Present and future of metastatic colorectal cancer treatment: A review of new candidate targets. World J Gastroenterol 2017; 23(26): 4675-4688 |
URL |
http://www.wjgnet.com/1007-9327/full/v23/i26/4675.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v23.i26.4675 |