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8/10/2017 11:54:13 PM | Browse: 865 | Download: 1488
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 33308
Country United Kingdom
Received
2017-02-07 10:48
Peer-Review Started
2017-02-07 14:14
To Make the First Decision
2017-03-27 11:23
Return for Revision
2017-03-28 15:44
Revised
2017-04-20 19:05
Second Decision
2017-05-11 13:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-19 04:32
Articles in Press
2017-05-19 04:32
Publication Fee Transferred
2017-06-14 03:39
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-17 07:39
Publish the Manuscript Online
2017-08-10 23:54
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer
Manuscript Source Unsolicited Manuscript
All Author List Michael Davidson, Ian Chau, David Cunningham, Komel Khabra, Timothy Iveson, Tamas Hickish, Matthew Seymour and Naureen Starling
Funding Agency and Grant Number
Corresponding Author Dr. Naureen Starling, Royal Marsden Hospital NHS Foundation Trust, London and Surrey, Fulham Road, London SM25PT, United Kingdom. naureen.starling@rmh.nhs.uk
Key Words Oesophageal cancer; Adenocarcinoma; Chemotherapy; Squamous; Pooled analysis
Core Tip There is a lack of published data on differential treatment response according to histology in oesophageal cancer. This paper shows improved response rates with first-line chemotherapy and a trend towards improved survival in adenocarcinoma compared to squamous cell carcinoma (SCC). It is increasingly recognised that these histological subtypes represent discrete disease entities with divergent treatment pathways in both the early stage and advanced settings. Novel treatments in SCC remain sparse and there are few dedicated trials in this subtype. This data highlights the poor outcomes seen with chemotherapy alone and the need for further research, particularly for SCC.
Publish Date 2017-08-10 23:54
Citation Davidson M, Chau I, Cunningham D, Khabra K, Iveson T, Hickish T, Seymour M, Starling N. Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer. World J Gastrointest Oncol 2017; 9(8): 333-340
URL http://www.wjgnet.com/1948-5204/full/v9/i8/333.htm
DOI http://dx.doi.org/10.4251/wjgo.v9.i8.333
Full Article (PDF) WJGO-9-333.pdf
Full Article (Word) WJGO-9-333.doc
Manuscript File 33308-Review.docx
Answering Reviewers 33308-Answering reviewers.pdf
Audio Core Tip 33308-Audio core tip.m4a
Biostatistics Review Certificate 33308-Biostatistics statement.pdf
Clinical Trial Registration Statement 33308_signed declaration_1218.pdf
Conflict-of-Interest Disclosure Form 33308-Conflict-of-interest statement.pdf
Copyright License Agreement 33308-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 33308-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 33308-Institutional review board statement.pdf
Peer-review Report 33308-Peer-review(s).pdf
Scientific Misconduct Check 33308-Scientific misconduct check.pdf
Scientific Editor Work List 33308-Scientific editor work list.pdf