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9/7/2017 8:51:55 AM | Browse: 1120 | Download: 1908
Publication Name World Journal of Gastroenterology
Manuscript ID 33788
Country/Territory Denmark
Received
2017-03-02 08:30
Peer-Review Started
2017-03-03 19:24
To Make the First Decision
2017-04-21 10:04
Return for Revision
2017-04-27 20:27
Revised
2017-05-30 08:29
Second Decision
2017-07-06 07:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-12 06:07
Articles in Press
2017-07-12 06:07
Publication Fee Transferred
2017-07-30 06:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-09-04 02:58
Publish the Manuscript Online
2017-09-07 08:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases
Manuscript Source Unsolicited Manuscript
All Author List Morten L Halling, Jens Kjeldsen, Torben Knudsen, Jan Nielsen and Lars Koch-Hansen
Funding Agency and Grant Number
Corresponding Author Morten L Halling, MD, Department of Gastroenterology and Hepatology, Hospital of Southwest Jutland, Medicinsk Gastroenterologisk Afdeling, Sydvestjysk Sygehus, Finsensgade 35, 6700 Esbjerg, Denmark. mortenhalling@gmail.com
Key Words Immune mediated diseases; Ulcerative colitis; Risk; Prevalence; Registry; Chronic inflammatory diseases; Autoimmune diseases; Inflammatory bowel disease; Crohn’s disease; Extraintestinal manifestations
Core Tip Essential to inflammatory bowel disease (IBD) pathogenesis are environmental factors, altered gut microbiota and genetic susceptibility. The latter causing impairment of barrier function, autophagy, and Th1, 2 and 17 cell responses. Interestingly, these mechanisms are also thought important in other immune mediated diseases, as is the overlap of susceptibility genes. Besides the classic extraintestinal manifestations, we found a variety of immune mediated diseases to be more frequent in individuals with IBD. Physicians should be aware of this when treating these patients. Furthermore, these findings support the hypothesis that immune mediated diseases may have overlapping pathogeneses. Thus, understanding IBD might help us understand other immune mediated diseases and vice versa.
Publish Date 2017-09-07 08:51
Citation Halling ML, Kjeldsen J, Knudsen T, Nielsen J, Koch Hansen L. Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases. World J Gastroenterol 2017; 23(33): 6137-6146
URL http://www.wjgnet.com/1007-9327/full/v23/i33/6137.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i33.6137
Full Article (PDF) WJG-23-6137.pdf
Full Article (Word) WJG-23-6137.doc
Manuscript File 33788-Review.docx
Answering Reviewers 33788-Answering reviewers.pdf
Audio Core Tip 33788-Audio core tip.mp3
Biostatistics Review Certificate 33788-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 33788-Conflict-of-interest statement.pdf
Copyright License Agreement 33788-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 33788_33788_Grant application KJF.doc
Signed Informed Consent Form(s) or Document(s) 33788_33788_Informed consent statement.docx
Institutional Review Board Approval Form or Document 33788-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 33788-Language certificate.pdf
Supplementary Material 33788-Supplementary material.pdf
Peer-review Report 33788-Peer-review(s).pdf
Scientific Misconduct Check 33788-Scientific misconduct check.pdf
Scientific Editor Work List 33788-Scientific editor work list.pdf