Publication Name	World Journal of Orthopedics
Manuscript ID	34085
Country	United States

Received	2017-03-27 09:08
Peer-Review Started	2017-03-28 18:33
To Make the First Decision	2017-04-17 09:33
Return for Revision	2017-05-04 22:35
Revised	2017-07-19 01:54
Second Decision	2017-07-28 05:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-08-02 20:42
Articles in Press	2017-08-02 20:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-21 03:00
Publish the Manuscript Online	2017-10-18 02:31

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Systematic Reviews
Article Title	Scaffolds based therapy for osteochondral lesions of the talus: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Yoshiharu Shimozono, Youichi Yasui, Andrew W Ross, Wataru Miyamoto and John G Kennedy
Funding Agency and Grant Number
Corresponding Author	John G Kennedy, Hospital for Special Surgery, 523 East 72nd Street, Suite 507, New York, NY 10021, United States. kennedyj@hss.edu
Key Words	Scaffold; Ankle; Talar osteochondral lesion; Systematic review; Cartilage
Core Tip	This systematic review demonstrated that scaffold-based therapy for lesions of the talus (OLT) may produce favorable clinical outcomes. However, 96% of included studies were classified into the category of poor level of evidence and no papers were of good methodological quality. Therefore, careful attention should be paid when evaluating scaffold-based therapy for OLT. In addition, large variability and underreporting of clinical data between studies made it difficult to reliably compare the results. Further well-designed studies are necessary to determine the effectiveness of scaffold-based therapy for OLT, especially when compared to the available traditional treatments.
Publish Date	2017-10-18 02:31
Citation	Shimozono Y, Yasui Y, Ross AW, Miyamoto W, Kennedy JG. Scaffolds based therapy for osteochondral lesions of the talus: A systematic review. World J Orthop 2017; 8(10): 798-808
URL	http://www.wjgnet.com/2218-5836/full/v8/i10/798.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i10.798

Full Article (PDF)	WJO-8-798.pdf
Full Article (Word)	WJO-8-798.doc
Manuscript File	34085-Review.docx
Answering Reviewers	34085-Answering reviewers.pdf
Audio Core Tip	34085-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	34085-Conflict-of-interest statement.pdf
Copyright License Agreement	34085-Copyright assignment.pdf
Peer-review Report	34085-Peer-review(s).pdf
Scientific Misconduct Check	34085-Scientific misconduct check.pdf
Scientific Editor Work List	34085-Scientific editor work list.pdf