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Publication Name World Journal of Gastroenterology
Manuscript ID 34207
Country/Territory United States
Received
2017-04-10 13:48
Peer-Review Started
2017-04-11 10:21
To Make the First Decision
2017-04-21 09:36
Return for Revision
2017-04-24 16:04
Revised
2017-05-04 03:31
Second Decision
2017-06-12 05:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-06-19 09:18
Articles in Press
2017-06-19 09:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-08-02 07:35
Publish the Manuscript Online
2017-08-14 04:00
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Systematic review of giant gastric lipomas reported since 1980 and report of two new cases in a review of 117110 esophagogastroduodenoscopies
Manuscript Source Invited Manuscript
All Author List Mitchell S Cappell, Charlton E Stevens and Mitual Amin
ORCID
Author(s) ORCID Number
Mitchell S Cappell http://orcid.org/0000-0003-3445-5428
Charlton E Stevens http://orcid.org/0000-0002-9036-1146
Mitual Amin http://orcid.org/0000-0002-0558-2615
Funding Agency and Grant Number
Corresponding Author Mitchell S Cappell, MD, PhD, Chief Doctor, Division of Gastroenterology and Hepatology, William Beaumont Hospital, MOB #602, 3535 W. Thirteen Mile Rd, Royal Oak, MI 48073, United States. mscappell@yahoo.com
Key Words Esophagogastroduodenoscopy Lipoma; Gastric; Giant; Melena; Upper gastrointestinal bleeding; Systematic review
Core Tip Systematic literature review of giant ga­stric lipomas revealed 32 reported cases since 1980, with 2 new cases reported among 117110 esophagogastroduodenoscopies. Two authors inde­pendently reviewed literature, and decided by consensus which articles to incorporate. Average-patient-age = 54.5 ± 17.0 years (males = 68.8%). Mean-maximal-lipoma-diameter = 7.9 cm ± 4.1 cm. Lipoma locations: antrum-17, antrum and other gastric segments-7, other-8. Lipomas were submucosal-92%, subserosal-8%. Presentations included: acute up­per gastrointestinal (UGI) bleeding-19, abdominal pain-5, nausea/vomiting-5, asymptomatic-3. esop­hagogastroduodenoscopy was extremely helpful diagnostically; findings included: yellowish hue, well-demarcated margins, and smooth overlying mucosa. Endoscopic biopsies were infrequently diagnostic. Twenty of 21 abdominal CTs demonstrated characteristic lipoma findings: well-circumscribed, submucosal, and homogeneous mass with fat attenuation. Endoscopic-ultrasound showed characteristic findings in 80%. All patients underwent successful therapy without major complications/mortality, including: laparotomy-with-full-thickness-gastric-wall-resections-26; and other-6. Two newly reported patients presented with severe UGI bleeding from giant, ulcerated, gastric lipomas. This review may help standardize work-up of these patients.
Publish Date 2017-08-14 04:00
Citation Cappell MS, Stevens CE, Amin M. Systematic review of giant gastric lipomas reported since 1980 and report of two new cases in a review of 117110 esophagogastroduodenoscopies. World J Gastroenterol 2017; 23(30): 5619-5633
URL http://www.wjgnet.com/1007-9327/full/v23/i30/5619.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i30.5619
Full Article (PDF) WJG-23-5619.pdf
Full Article (Word) WJG-23-5619.doc
Manuscript File 34207-Review.docx
Answering Reviewers 34207-Answering reviewers.pdf
Audio Core Tip 34207-Audio core tip.mp3
Biostatistics Review Certificate 34207-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 34207-Conflict-of-interest statement.pdf
Copyright License Agreement 34207-Copyright assignment.pdf
Supplementary Material 34207_Giantgastriclipoma-IRBapprovalexemption.docx
Peer-review Report 34207-Peer-review(s).pdf
Scientific Misconduct Check 34207-Scientific misconduct check.pdf
Scientific Editor Work List 34207-Scientific editor work list.pdf