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10/16/2017 7:24:27 AM | Browse: 864 | Download: 1257
Publication Name World Journal of Gastroenterology
Manuscript ID 34361
Country China
Received
2017-04-17 12:23
Peer-Review Started
2017-04-27 18:00
To Make the First Decision
2017-06-22 05:59
Return for Revision
2017-06-27 08:48
Revised
2017-07-20 16:41
Second Decision
2017-09-05 09:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-05 18:44
Articles in Press
2017-09-05 18:44
Publication Fee Transferred
2017-09-08 16:40
Edit the Manuscript by Language Editor
2017-09-21 06:23
Typeset the Manuscript
2017-09-27 01:49
Publish the Manuscript Online
2017-10-16 07:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Adipose-derived stromal cells resemble bone marrow stromal cells in hepatocyte differentiation potential in vitro and in vivo
Manuscript Source Unsolicited Manuscript
All Author List Li-Juan Xu, Shu-Fang Wang, De-Qing Wang, Lian-Jun Ma, Zheng Chen, Qian-Qian Chen, Jun Wang and Li Yan
ORCID
Author(s) ORCID Number
Li-Juan Xu http://orcid.org/0000-0002-2924-7213
Shu-Fang Wang http://orcid.org/0000-0001-5768-9687
De-Qing Wang http://orcid.org/0000-0002-5559-0541
Lian-Jun Ma http://orcid.org/0000-0002-4512-1688
Zheng Chen http://orcid.org/0000-0002-1253-6254
Qian-Qian Chen http://orcid.org/0000-0001-8527-1018
Jun Wang http://orcid.org/0000-0002-6757-0337
Li Yan http://orcid.org/0000-0001-8881-1921
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 30900669
National Natural Science Foundation of China 81473271
Technology Nova Plan of Beijing City 2011117
Postdoctoral Science Foundation 2016T90994
Corresponding Author Li Yan, MD, PhD, Chief Doctor, Department of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, No.28 Wanshou Road, Haidian Distict, Beijing 100853, China. yanlifmu@126.com
Key Words Adipose-derived stromal cells; Bone marrow stromal cells; Cell differentiation; Hepatocyte differentiation
Core Tip Our study investigated whether mesenchymal stem cells from different sources, including adipose-derived stromal cells (ADSCs) and bone marrow stromal cells (BMSCs), have similar hepatic differentiation potential. And our finding found that adipose-derived stromal cells resemble bone marrow stromal cells in their hepatocyte differentiation potential in vitro and in vivo. Because ADSCs are obtained more easily and less invasive than BMSCs. Therefore, ADSCs might be more suitable seed cells for cell transplant or liver tissue engineering. Besides, we developed a new protocol of preparing mouse BMSCs and established a new hepatic induction system.
Publish Date 2017-10-16 07:24
Citation Xu LJ, Wang SF, Wang DQ, Ma LJ, Chen Z, Chen QQ, Wang J, Yan L. Adipose-derived stromal cells resemble bone marrow stromal cells in hepatocyte differentiation potential in vitro and in vivo. World J Gastroenterol 2017; 23(38): 6973-6982
URL http://www.wjgnet.com/1007-9327/full/v23/i38/6973.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i38.6973
Full Article (PDF) WJG-23-6973.pdf
Full Article (Word) WJG-23-6973.doc
Manuscript File 34361-Review.docx
Answering Reviewers 34361-Answering reviewers.pdf
Audio Core Tip 34361-Audio core tip.mp3
Biostatistics Review Certificate 34361-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 34361-Conflict-of-interest statement.pdf
Copyright License Agreement 34361-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 34361-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 34361-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 34361-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 34361-Language certificate.pdf
Supplementary Material 34361-Supplementary material.docx
Peer-review Report 34361-Peer-review(s).pdf
Scientific Misconduct Check 34361-Scientific misconduct check.pdf
Scientific Editor Work List 34361-Scientific editor work list.pdf