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9/21/2017 7:51:53 AM | Browse: 627 | Download: 817
Publication Name World Journal of Gastroenterology
Manuscript ID 34604
Country Japan
Received
2017-05-18 01:02
Peer-Review Started
2017-05-18 07:14
To Make the First Decision
2017-06-22 00:39
Return for Revision
2017-06-23 10:37
Revised
2017-07-06 06:38
Second Decision
2017-08-02 00:37
Accepted by Journal Editor-in-Chief
2017-08-04 08:31
Accepted by Company Editor-in-Chief
2017-08-08 05:51
Articles in Press
2017-08-08 05:51
Publication Fee Transferred
2017-08-10 01:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-09-20 01:06
Publish the Manuscript Online
2017-09-21 07:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Acquired amegakaryocytic thrombocytopenia previously diagnosed as idiopathic thrombocytopenic purpura in a patient with hepatitis C virus infection
Manuscript Source Unsolicited Manuscript
All Author List Shojiro Ichimata, Mikiko Kobayashi, Kohei Honda, Soichiro Shibata, Akihiro Matsumoto and Hiroyuki Kanno
ORCID
Author(s) ORCID Number
Shojiro Ichimata http://orcid.org/0000-0002-7305-8137
Mikiko Kobayashi http://orcid.org/0000-0003-2757-6117
Kohei Honda http://orcid.org/0000-0002-7613-1635
Soichiro Shibata http://orcid.org/0000-0002-0972-5791
Akihiro Matsumoto http://orcid.org/0000-0001-6453-8529
Hiroyuki Kanno http://orcid.org/0000-0002-3200-9304
Funding Agency and Grant Number
Corresponding Author Mikiko Kobayashi, MD, PhD, Department of Pathology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. mikko@shinshu-u.ac.jp
Key Words Acquired amegakaryocytic thrombocytopenia, Anti-thrombopoietin receptor (c-Mpl) autoantibodies, Hepatitis C virus, Idiopathic thrombocytopenic purpura, and Thrombocytopenia
Core Tip Thrombocytopenia occurs frequently in patients with hepatitis C virus (HCV) infection. Acquired amegakaryocytic thrombocytopenia (AAMT) is one of the causes of severe thrombocytopenia. The exact mechanisms of AAMT have not been fully elucidated. However, patients with autoantibodies to thrombopoietin receptor (c-Mpl) develop AAMT. Similarly, autoantibodies are sometimes generated in patients with HCV infection. Here, we report the first case of a patient with HCV infection who later developed AAMT with autoantibodies to c-Mpl. AAMT with autoantibodies to c-Mpl may be one of the causes of thrombocytopenia in patients with HCV infection.
Publish Date 2017-09-21 07:51
Citation Ichimata S, Kobayashi M, Honda K, Shibata S, Matsumoto A, Kanno H. Acquired amegakaryocytic thrombocytopenia previously diagnosed as idiopathic thrombocytopenic purpura in a patient with hepatitis C virus infection. World J Gastroenterol 2017; 23(35): 6540-6545
URL http://www.wjgnet.com/1007-9327/full/v23/i35/6540.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i35.6540
Full Article (PDF) WJG-23-6540.pdf
Full Article (Word) WJG-23-6540.doc
Manuscript File 34604-Review.docx
Answering Reviewers 34604-Answering reviewers.pdf
Audio Core Tip 34604-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34604-Conflict-of-interest statement.pdf
Copyright License Agreement 34604-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 34604-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 34604-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 34604-Language certificate.pdf
Peer-review Report 34604-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 34604-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 34604-Scientific misconduct check.pdf
Scientific Editor Work List 34604-Scientific editor work list.pdf