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9/14/2017 3:13:08 AM | Browse: 35 | Download: 66
Publication Name World Journal of Gastroenterology
Manuscript ID 34896
Country of Manuscript Source China
Received
2017-06-07 00:29
Peer-Review Started
2017-06-08 07:02
To Make the First Decision
2017-07-13 05:02
Return for Revision
2017-07-17 11:55
Revised
2017-07-27 11:43
Second Decision
2017-08-15 07:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-08-15 15:11
Articles in Press
2017-08-15 15:11
Publication Fee Transferred
2017-08-18 09:21
Edit the Manuscript by Language Editor
2017-08-31 03:25
Typeset the Manuscript
2017-09-07 08:32
Publish the Manuscript Online
2017-09-14 03:13
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Natural history of covert hepatic encephalopathy: An observational study of 366 cirrhotic patients
Manuscript Source Unsolicited Manuscript
All Author List An-Jiang Wang, A-Ping Peng, Bi-Min Li, Na Gan, Li Pei, Xue-Lian Zheng, Jun-Bo Hong, Hai-Ying Xiao, Jia-Wei Zhong and Xuan Zhu
ORCID
Author ORCID Number
An-Jiang Wang http://orcid.org/0000-0001-6670-6645
A-Ping Peng http://orcid.org/0000-0002-2826-509X
Bi-Min Li http://orcid.org/0000-0001-7099-0343
Na Gan http://orcid.org/0000-0003-3457-3213
Li Pei http://orcid.org/0000-0002-7733-9913
Xue-Lian Zheng http://orcid.org/0000-0003-0005-3615
Jun-Bo Hong http://orcid.org/0000-0001-6924-3033
Hai-Ying Xiao http://orcid.org/0000-0002-6567-1046
Jia-Wei Zhong http://orcid.org/0000-0001-9964-302x
Xuan Zhu http://orcid.org/0000-0003-2463-3112
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Planning Project of Health and Family Planning Commission of Jiangxi Province 20171022
National Natural Science Fund of China 81460122
Project in the Science and Technology Pillar Program of Jiangxi Provincial Department of Science and Technology 20161BBG70166
Jiangxi Provincial Outstanding Young Talent Program 20171BCB23085
Natural Science Fund of Jiangxi Province For Young Scholars 20171BAB215008
Correspondence To Xuan Zhu, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Nanchang University, 17 Yongwai Zheng Street, Nanchang 330006, Jiangxi Province, China. ndyfy0326@ncu.edu.cn
Keywords Covert hepatic encephalopathy; Overt hepatic encephalopathy; Natural history; Liver cirrhosis
Core Tip Covert hepatic encephalopathy (CHE) was prevalent in clinically-stable cirrhosis in the tertiary care hospital. A history of overt hepatic encephalopathy (OHE) was the only risk factor for CHE in patients with OHE history, while a high model for end-stage liver disease score was the only risk factor for those without OHE history. Natural history of CHE in the absence of medication intervention included development of complications, persistence or spontaneous resolution of CHE. Triage of patients based on predictors for exacerbation and resolution, rather than the degree of impairment in daily work productivity or quality of life, could make clinical management of CHE more cost-effective.
Publish Date 2017-09-14 03:13
Citation Wang AJ, Peng AP, Li BM, Gan N, Pei L, Zheng XL, Hong JB, Xiao HY, Zhong JW, Zhu X. Natural history of covert hepatic encephalopathy: An observational study of 366 cirrhotic patients. World J Gastroenterol 2017; 23(34): 6321-6329
Url http://www.wjgnet.com/1007-9327/full/v23/i34/6321.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i34.6321
Full Article (PDF) WJG-23-6321.pdf
Full Article (Word) WJG-23-6321.doc
Revised Manuscript 34896-Review.docx
Peer-review Report 34896-Peer-review(s).pdf
Answering Reviewers 34896-Answering reviewers.pdf
Scientific Misconduct Check 34896-Scientific misconduct check.pdf
Scientific Editor Work List 34896-Scientific editor work list.pdf
Audio Core Tip 34896-Audio core tip.mp3
Biostatistics Review Certificate 34896-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 34896-Conflict-of-interest statement.pdf
Copyright License Agreement 34896-Copyright assignment.pdf
Data Sharing Statement 34896-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 34896-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 34896-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 34896-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 34896-Language certificate.pdf
Scientific Research Process 34896-Scientific research process.pdf