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12/14/2017 12:28:19 AM | Browse: 449 | Download: 224
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 35175
Country/Territory United States
Received
2017-06-26 01:48
Peer-Review Started
2017-06-27 08:59
To Make the First Decision
2017-08-07 01:03
Return for Revision
2017-08-07 02:38
Revised
2017-08-24 14:24
Second Decision
2017-09-06 08:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-16 19:03
Articles in Press
2017-09-16 19:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-12-08 03:05
Publish the Manuscript Online
2017-12-14 00:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Neoadjuvant therapy for resectable pancreatic cancer
Manuscript Source Unsolicited Manuscript
All Author List Sheikh Hasibur Rahman, Robin Urquhart and Michele Molinari
ORCID
Author(s) ORCID Number
Sheikh Hasibur Rahman http://orcid.org/0000-0001-7877-2703
Robin Urquhart http://orcid.org/0000-0001-8864-5716
Michele Molinari http://orcid.org/0000-0001-8864-5719
Funding Agency and Grant Number
Corresponding author Michele Molinari, MD, MSc, Senior Scientist, Surgeon, Department of Surgery, University of Pittsburgh Medical Center, 3459 Fifth Avenue, N758, Pittsburgh, PA 15213, United States. molinarim@upmc.edu
Keywords Pancreatic adenocarcinoma; Neoadjuvant chemotherapy; Neoadjuvant chemoradiation therapy; Meta-analysis; Decision analysis; Borderline resectable; Locally advanced; Randomized controlled trial; Phase Ⅰ trial; Phase Ⅱ trial; Phase Ⅲ trial
Core Tip The use of neoadjuvant therapy for patients with resectable pancreatic cancer (PC) has been used by an increasing number of cancer centers around the world. The main rationale of using neoadjuvant therapies in resectable PC is the hope that patients’ likelihood of long-term overall survival will benefit from the chemo or chemoradiation therapy administered when their overall conditions allow them to tolerate the treatment. At this time, there is no phase Ⅲ trial to support the use of neoadjuvant therapies in resectable PC. Without strong scientific evidence supporting the theoretical advantages of neoadjuvant therapies, these potential benefits might turn out not to be worth the risk of tumors progression while waiting for surgery.
Publish Date 2017-12-14 00:28
Citation Rahman SH, Urquhart R, Molinari M. Neoadjuvant therapy for resectable pancreatic cancer. World J Gastrointest Oncol 2017; 9(12): 457-465
Url http://www.wjgnet.com/1948-5204/full/v9/i12/457.htm
DOI http://dx.doi.org/10.4251/wjgo.v9.i12.457
Full Article (PDF) WJGO-9-457.pdf
Full Article (Word) WJGO-9-457.doc
Manuscript File 35175-Review.docx
Answering Reviewers 35175-Answering reviewers.pdf
Audio Core Tip 35175-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 35175-Conflict-of-interest statement.pdf
Copyright License Agreement 35175-Copyright assignment.pdf
Supplementary Material 35175-Supplementary-Material-revision.docx
Peer-review Report 35175-Peer-review(s).pdf
Scientific Misconduct Check 35175-Scientific misconduct check.pdf
Scientific Editor Work List 35175-Scientific editor work list.pdf