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11/17/2017 9:05:21 AM | Browse: 1191 | Download: 1376
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 35335
Country Germany
Received
2017-07-17 00:21
Peer-Review Started
2017-07-19 08:07
To Make the First Decision
2017-08-07 00:42
Return for Revision
2017-08-07 08:06
Revised
2017-08-17 17:57
Second Decision
2017-08-28 09:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-05 04:08
Articles in Press
2017-09-05 04:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-14 03:32
Publish the Manuscript Online
2017-11-17 09:05
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Clinical Trials Study
Article Title Value of histomorphometric tumour thickness and smoothelin for conventional m-classification in early oesophageal adenocarcinoma
Manuscript Source Invited Manuscript
All Author List Katharina Endhardt, Bruno Märkl, Andreas Probst, Tina Schaller and Daniela Aust
ORCID
Author(s) ORCID Number
Katharina Endhardt http://orcid.org/0000-0002-1847-2394
Bruno Märkl http://orcid.org/0000-0002-7704-850x
Andreas Probst http://orcid.org/0000-0002-1486-9298
Tina Schaller http://orcid.org/0000-0003-2295-8810
Daniela Aust http://orcid.org/0000-0002-4867-8852
Funding Agency and Grant Number
Corresponding Author Bruno Märkl, MD, Institute of Pathology, Klinikum Augsburg, Stenglinstr 2, Augsburg 86156, Germany. bruno.maerkl@klinikum-augsburg.de
Key Words Endoscopic submucosal dissection; Muscularis mucosae; Adenocarcinoma; Barrett’s carcinoma; Smoothelin
Core Tip The aim of this study was to determine whether histomorphometric measurement of tumor thickness and immunohistochemical staining for smoothelin facilitate the exact pT substaging in early oesophageal adenocarcinoma. Our data showed that there is clear cut-off of 1000 µm to distinguish advanced early lesions (M4/sm1) from such lesions that do not reach the deep muscularis mucosae or the submucosa. Moreover, smoothelin staining is of help to distinguish the superficial from the deep muscularis mucosa by different staining intensities. Therfore, both methods could be shown to be of help for the often challenging task to T-classify early oesophageal adenocarcinomas.
Publish Date 2017-11-17 09:05
Citation Endhardt K, Märkl B, Probst A, Schaller T, Aust D. Value of histomorphometric tumour thickness and smoothelin for conventional m-classification in early oesophageal adenocarcinoma. World J Gastrointest Oncol 2017; In press
URL http://www.wjgnet.com/1948-5204/full/v9/i11/444.htm
DOI http://dx.doi.org/10.4251/wjgo.v9.i11.444
Full Article (PDF) WJGO-9-444.pdf
Full Article (Word) WJGO-9-444.doc
Manuscript File 35335-Review.docx
Answering Reviewers 35335-Answering reviewers.pdf
Audio Core Tip 35335-Audio core tip.mp3
Biostatistics Review Certificate 35335-Biostatistics statement.pdf
Clinical Trial Registration Statement 35335-Clinical-Trial-Registration-Statement-revision.pdf
Conflict-of-Interest Disclosure Form 35335-Conflict-of-interest statement.pdf
Copyright License Agreement 35335-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 35335-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Signed Informed Consent Form(s) or Document(s) 35335-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 35335-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 35335-Language certificate.pdf
Peer-review Report 35335-Peer-review(s).pdf
Scientific Editor Work List 35335-Scientific editor work list.pdf
Scientific Editor Work List 35335-Scientific misconduct check.pdf