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10/16/2017 7:24:27 AM | Browse: 649 | Download: 767
Publication Name World Journal of Gastroenterology
Manuscript ID 35647
Country/Territory China
Received
2017-08-02 00:09
Peer-Review Started
2017-08-02 12:07
To Make the First Decision
2017-08-10 00:15
Return for Revision
2017-08-10 08:43
Revised
2017-08-19 06:07
Second Decision
2017-09-05 09:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-05 18:23
Articles in Press
2017-09-05 18:23
Publication Fee Transferred
2017-09-08 00:13
Edit the Manuscript by Language Editor
2017-09-19 01:58
Typeset the Manuscript
2017-09-27 02:00
Publish the Manuscript Online
2017-10-16 07:24
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Mitofusin-2 mediated mitochondrial Ca2+ uptake 1/2 induced liver injury in rat remote ischemic perconditioning liver transplantation and alpha mouse liver-12 hypoxia cell line models
Manuscript Source Unsolicited Manuscript
All Author List Ruo-Peng Liang, Jun-Jun Jia, Jian-Hui Li, Ning He, Yan-Fei Zhou, Li Jiang, Tao Bai, Hai-Yang Xie, Lin Zhou and Yu-Ling Sun
ORCID
Author(s) ORCID Number
Ruo-Peng Liang http://orcid.org/orcid.org/0000-0002-3789-1666
Jun-Jun Jia http://orcid.org/orcid.org/0000-0002-1495-2390
Jian-Hui Li http://orcid.org/orcid.org/0000-0002-9662-0583
Ning He http://orcid.org/orcid.org/0000-0002-2768-0021
Yan-Fei Zhou http://orcid.org/orcid.org/0000-0003-0471-3190
Li Jiang http://orcid.org/orcid.org/0000-0002-6461-3354
Tao Bai http://orcid.org/orcid.org/0000-0002-3817-5602
Hai-Yang Xie http://orcid.org/orcid.org/0000-0002-6913-9284
Lin Zhou http://orcid.org/orcid.org/0000-0001-5689-3512
Yu-Ling Sun http://orcid.org/orcid.org/0000-0001-5289-4673
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Innovation Talents Support Plan, Department of Education, Henan Province, China No. 17HASTIT044
China Postdoctoral Science Foundation No. 2017M610374
Corresponding Author Yu-Ling Sun, MD, PhD, Professor, Surgeon, Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital, Zhengzhou University, 1st Jianshe East Road, Zhengzhou, Zhengzhou 450052, Henan, China. ylsun@zzu.edu.cn
Key Words Remote ischemic per-conditioning; Ischemia reperfusion injury; Ca2+; Mitofusin-2; Mitochondrial Ca2+ uniporter
Core Tip Compared to the orthotopic liver transplantation, remote ischemic preconditioning (RIC) model can significantly improve liver functions. But knowledge of its mechanism remains largely unknown. This research is the first to prove the protective mechanism of mitofusin-2-mitochondrial Ca2+ uptake 1/2 axis by affecting the metabolism of intracellular calcium in RIC model of liver transplantation and revalidate it in alpha mouse liver-12 hypoxia cell lines.
Publish Date 2017-10-16 07:24
Citation Liang RP, Jia JJ, Li JH, He N, Zhou YF, Jiang L, Bai T, Xie HY, Zhou L, Sun YL. Mitofusin-2 mediated mitochondrial Ca2+ uptake 1/2 induced liver injury in rat remote ischemic perconditioning liver transplantation and alpha mouse liver-12 hypoxia cell line models. World J Gastroenterol 2017; 23(38): 6995-7008
URL http://www.wjgnet.com/1007-9327/full/v23/i38/6995
DOI http://dx.doi.org/10.3748/wjg.v23.i38.6995
Full Article (PDF) WJG-23-6995.pdf
Full Article (Word) WJG-23-6995.doc
Manuscript File 35647-Review.doc
Answering Reviewers 35647-Answering reviewers.pdf
Audio Core Tip 35647-Audio core tip.mp3
Biostatistics Review Certificate 35647-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 35647-Conflict-of-interest statement.pdf
Copyright License Agreement 35647-Copyright assignment.pdf
Data Sharing Statement 35647-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 35647-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 35647-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 35647-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 35647-Language certificate.pdf
Scientific Research Process 35647-Scientific research process.pdf
Supplementary Material 35647-Supplementary material.pdf
Peer-review Report 35647-Peer-review(s).pdf
Scientific Misconduct Check 35647-Scientific misconduct check.pdf
Scientific Editor Work List 35647-Scientific editor work list.pdf