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1/19/2018 9:46:49 AM | Browse: 974 | Download: 1154
Publication Name World Journal of Gastroenterology
Manuscript ID 36562
Country China
Received
2017-10-25 00:41
Peer-Review Started
2017-10-25 06:54
To Make the First Decision
2017-11-22 01:08
Return for Revision
2017-11-27 11:11
Revised
2017-12-18 15:14
Second Decision
2017-12-26 11:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-26 19:23
Articles in Press
2017-12-26 19:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-12-30 12:39
Typeset the Manuscript
2018-01-15 08:11
Publish the Manuscript Online
2018-01-19 09:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Optimization of hepatobiliary phase delay time of Gd-EOB-DTPA-enhanced magnetic resonance imaging for identification of hepatocellular carcinoma in patients with cirrhosis of different degrees of severity
Manuscript Source Invited Manuscript
All Author List Jian-Wei Wu, Yue-Cheng Yu, Xian-Li Qu, Yan Zhang and Hong Gao
ORCID
Author(s) ORCID Number
Jian-Wei Wu http://orcid.org/0000-0002-8131-636X
Yue-Cheng Yu http://orcid.org/0000-0003-3480-1829
Xian-Li Qu http://orcid.org/0000-0002-0693-5670
Yan Zhang http://orcid.org/0000-0001-6911-2826
Hong Gao http://orcid.org/0000-0001-5400-6668
Funding Agency and Grant Number
Corresponding Author Yue-Cheng Yu, MD, PhD, Chief Doctor, Professor, Liver Disease Center, Bayi Hospital, Nanjing University of Chinese Medicine, No.34, Section 34, Yang Gong Jing, Qinhuai Region, Nanjing 210002, Jiangsu, China. gslsycy@163.com
Key Words Magnetic resonance imaging; Gd-EOB-DTPA; Hepatobiliary phase; Delay time; Hepatocellular carcinoma; Cirrhosis; Optimization
Core Tip In order to optimize the hepatobiliary phase delay time (HBP-DT) of Gd-EOB-DTPA-enhanced magnetic resonance imaging for more efficient identification of hepatocellular carcinoma (HCC) in cirrhosis of different degrees of severity, we analyzed the signal intensity and ratios between liver parenchyma and HCC, and the percentages of HCC visibility at a series of HBP-DT points in those patients. The severity of cirrhosis was shown to negatively influence HCC visibility, but DT-10 is already enough and more efficient than longer DT to identify HCC in Child-Pugh (CP)-A and CP-B cirrhosis. DT-15 or longer DT seems more appropriate for HCC visibility in patients with CP-C cirrhosis.
Publish Date 2018-01-19 09:46
Citation Wu JW, Yu YC, Qu XL, Zhang Y, Gao H. Optimization of hepatobiliary phase delay time of Gd-EOB-DTPA-enhanced magnetic resonance imaging for identification of hepatocellular carcinoma in patients with cirrhosis of different degrees of severity. World J Gastroenterol 2018; 24(3): 415-423
URL http://www.wjgnet.com/1007-9327/full/v24/i3/415.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i3.415
Full Article (PDF) WJG-24-415.pdf
Full Article (Word) WJG-24-415.doc
Manuscript File 36562-Review.doc
Answering Reviewers 36562-Answering reviewers.pdf
Audio Core Tip 36562-Audio core tip.m4a
Biostatistics Review Certificate 36562-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 36562-Conflict-of-interest statement.pdf
Copyright License Agreement 36562-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 36562-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 36562-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 36562-Language certificate.pdf
Peer-review Report 36562-Peer-review(s).pdf
Scientific Misconduct Check 36562-Scientific misconduct check.pdf
Scientific Editor Work List 36562-Scientific editor work list.pdf