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1/7/2018 4:21:05 AM | Browse: 1209 | Download: 1732
Publication Name World Journal of Gastroenterology
Manuscript ID 36576
Country/Territory Italy
Received
2017-10-09 03:41
Peer-Review Started
2017-10-09 08:16
To Make the First Decision
2017-10-25 01:03
Return for Revision
2017-10-25 09:25
Revised
2017-11-13 17:45
Second Decision
2017-11-21 12:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-21 18:37
Articles in Press
2017-11-21 18:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
2017-11-29 20:57
Typeset the Manuscript
2017-12-23 15:06
Publish the Manuscript Online
2018-01-07 04:21
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis
Manuscript Source Invited Manuscript
All Author List Giuseppe Losurdo, Rossella Cubisino, Michele Barone, Mariabeatrice Principi, Gioacchino Leandro, Enzo Ierardi and Alfredo Di Leo
ORCID
Author(s) ORCID Number
Giuseppe Losurdo http://orcid.org/0000-0001-7038-3287
Rossella Cubisino http://orcid.org/0000-0001-5983-3726
Michele Barone http://orcid.org/0000-0001-8284-5127
Mariabeatrice Principi http://orcid.org/0000-0003-0545-5656
Gioacchino Leandro http://orcid.org/0000-0001-6624-4532
Enzo Ierardi http://orcid.org/0000-0001-7275-5080
Alfredo Di Leo http://orcid.org/0000-0003-2026-1200
Funding Agency and Grant Number
Corresponding Author Enzo Ierardi, MD, Professor, Section of Gastroenterology, Department of Emergency and Organ Transplantation, University “Aldo Moro”, Piazza Giulio Cesare 11, Bari 70124, Italy. e.ierardi@virgilio.it
Key Words Helicobacter pylori; probiotics; eradication; meta-analysis; breath test
Core Tip Despite several lines of evidence in the literature having demonstrated a pivotal role of probi­otics as adjunctive treatment for Helicobacter pylori (H. pylori) eradication, national and international guidelines do not have a uniform consensus about their clinical application. Many meta-analyses have confirmed that co-administration of probiotics may have a beneficial effect on the prevention of side effects and eradication rates. Herein, we found that probiotic monotherapy may eradicate H. pylori in 14% of cases. Lactobacilli, Saccharomyces boulardii and multistrain combinations eradicated the bacterium with a rate of 16%, 12% and 14%, respectively. Probiotics were significantly more effective than placebo (OR = 7.91).
Publish Date 2018-01-07 04:21
Citation Losurdo G, Cubisino R, Barone M, Principi M, Leandro G, Ierardi E, Di Leo A. Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis. World J Gastroenterol 2018; 24(1): 139-149
URL http://www.wjgnet.com/1007-9327/full/v24/i1/139.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i1.139
Full Article (PDF) WJG-24-139.pdf
Full Article (Word) WJG-24-139.doc
Manuscript File 36576-Review.doc
Answering Reviewers 36576-Answering reviewers.pdf
Audio Core Tip 36576-Audio core tip.m4a
Biostatistics Review Certificate 36576-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 36576-Conflict-of-interest statement.pdf
Copyright License Agreement 36576-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 36576-Non-Native-Speakers-of-English-Editing-Certificate-revision.pdf
Supplementary Material 36576-Supplementary Material.doc
Peer-review Report 36576-Peer-review(s).pdf
Scientific Misconduct Check 36576-Scientific misconduct check.pdf
Scientific Editor Work List 36576-Scientific editor work list.pdf