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1/19/2018 9:46:49 AM | Browse: 935 | Download: 841
Publication Name World Journal of Gastroenterology
Manuscript ID 36631
Country/Territory Germany
Received
2017-10-28 06:49
Peer-Review Started
2017-10-28 09:37
To Make the First Decision
2017-11-15 01:25
Return for Revision
2017-11-16 11:40
Revised
2017-12-01 08:28
Second Decision
2017-12-04 08:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-12-04 19:50
Articles in Press
2017-12-04 19:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-01-15 08:10
Publish the Manuscript Online
2018-01-19 09:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Beneficial long term effect of a phosphodiesterase-5-inhibitor in cirrhotic portal hypertension: A case report with 8 years follow-up
Manuscript Source Unsolicited Manuscript
All Author List Peter Deibert, Adhara Lazaro, Zoran Stankovic, Denise Schaffner, Martin Rössle and Wolfgang Kreisel
ORCID
Author(s) ORCID Number
Peter Deibert http://orcid.org/0000-0002-3291-884X
Adhara Lazaro http://orcid.org/0000-0001-9023-1387
Zoran Stankovic http://orcid.org/0000-0001-6265-3072
Denise Schaffner http://orcid.org/0000-0001-6173-9288
Martin Rössle http://orcid.org/0000-0002-1358-9163
Wolfgang Kreisel http://orcid.org/0000-0001-6884-0135
Funding Agency and Grant Number
Corresponding Author Wolfgang Kreisel, MD, Professor, Department of Internal Medicine, University of Freiburg, Hugstetter Str. 55, Freiburg 79106, Germany. wolfgang.kreisel@uniklinik-freiburg.de
Key Words Portal hypertension; Phosphodiesterase-5; Liver hemodynamics; Doppler sonography; Magnetic resonance imaging; Liver cirrhosis
Core Tip Non-selective beta-blockers are the mainstay of medical therapy for portal hypertension in liver cirrhosis. Inhibitors of phosphodiesterase-5 (PDE-5) reduce portal pressure in the acute setting by > 10%. This is the first report of a patient with liver cirrhosis showing that in long-term treatment with a PDE-5-inhibitor the positive effect on liver hemodynamics is maintained thus preventing further variceal bleeding.
Publish Date 2018-01-19 09:46
Citation Deibert P, Lazaro A, Stankovic Z, Schaffner D, Rössle M, Kreisel W. Beneficial long term effect of a phosphodiesterase-5-inhibitor in cirrhotic portal hypertension: A case report with 8 years follow-up. World J Gastroenterol 2018; 24(3): 438-444
URL http://www.wjgnet.com/1007-9327/full/v24/i3/438.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i3.438
Full Article (PDF) WJG-24-438.pdf
Full Article (Word) WJG-24-438.doc
Manuscript File 36631-Review.docx
Answering Reviewers 36631-Answering reviewers.pdf
Audio Core Tip 36631-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 36631-Conflict-of-interest statement.pdf
Copyright License Agreement 36631-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 36631-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 36631-Non-Native-Speakers-of-English-Editing-Certificate-revision.docx
Peer-review Report 36631-Peer-review(s).pdf
Scientific Editor Work List 36631-Scientific editor work list.pdf