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1/7/2018 4:21:05 AM | Browse: 987 | Download: 1671
Publication Name World Journal of Gastroenterology
Manuscript ID 36744
Country/Territory Spain
Received
2017-10-29 02:27
Peer-Review Started
2017-10-29 06:00
To Make the First Decision
2017-11-15 01:24
Return for Revision
2017-11-16 08:07
Revised
2017-11-22 14:43
Second Decision
2017-11-27 10:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-27 20:08
Articles in Press
2017-11-27 20:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-12-25 15:37
Publish the Manuscript Online
2018-01-07 04:21
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Genetics & Heredity
Manuscript Type Observational Study
Article Title HLA-DQ: Celiac disease vs inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Marta M Bosca-Watts, Miguel Minguez, Dolores Planelles, Samuel Navarro, Alejandro Rodriguez, Jesus Santiago, Joan Tosca and Francisco Mora
ORCID
Author(s) ORCID Number
Marta M Bosca-Watts http://orcid.org/0000-0001-7495-8797
Miguel Minguez http://orcid.org/0000-0003-0148-5938
Dolores Planelles http://orcid.org/0000-0001-6433-4825
Samuel Navarro http://orcid.org/0000-0001-5016-5653
Alejandro Rodriguez http://orcid.org/0000-0001-9445-4286
Jesus Santiago http://orcid.org/0000-0002-3219-0190
Joan Tosca http://orcid.org/0000-0003-1258-9513
Francisco Mora http://orcid.org/0000-0002-6044-5752
Funding Agency and Grant Number
Funding Agency Grant Number
Carlos III Institute CM07/00240
Corresponding Author Marta M Bosca-Watts, MD, PhD, Attending Doctor, Research Scientist, Staff Physician, IBD Unit, Digestive Disease Department of the University Clinic Hospital of Valencia, University of Valencia, C/ Blasco Ibañez 17, Valencia 46010, Spain. inflamatoriahcuv@gmail.com
Key Words Genetic predisposition; Celiac disease; Inflammatory bowel disease; Crohn’s disease; Human leucocyte antigen; Ulcerative colitis
Core Tip The higher risk for celiac disease (CeD) in inflammatory bowel disease (IBD) is controversial. Since the involvement of human leucocyte antigen (HLA)-DQ2 and -DQ8 antigens (HLA-CeD) in the susceptibility to CeD is clearly established and it has been accepted as a useful test to exclude CeD, we determined the frequency of HLA-CeD in IBD patients. We observed that HLA-CeD is not more frequent in IBD patients, with an even lower frequency of HLA-DQ2 and -DQ8 in ulcerative colitis and Crohn’s disease respectively. On the other hand, HLA-DQ2.2 was present in 34% of the Crohn’s disease patients and may constitute a genetic risk factor.
Publish Date 2018-01-07 04:21
Citation Bosca-Watts MM, Minguez M, Planelles D, Navarro S, Rodriguez A, Santiago J, Tosca J, Mora F. HLA-DQ: Celiac disease vs inflammatory bowel disease. World J Gastroenterol 2018; 24(1): 96-103
URL http://www.wjgnet.com/1007-9327/full/v24/i1/96.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i1.96
Full Article (PDF) WJG-24-96.pdf
Full Article (Word) WJG-24-96.doc
Manuscript File 36744-Review.docx
Answering Reviewers 36744-Answering reviewers.pdf
Audio Core Tip 36744-Audio core tip.m4a
Biostatistics Review Certificate 36744-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 36744-Conflict-of-interest statement.pdf
Copyright License Agreement 36744-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 36744-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 36744-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 36744-Institutional review board statement.pdf
Supplementary Material 36744-Supplementary-Material-revision.xps
Peer-review Report 36744-Peer-review(s).pdf
Scientific Misconduct Check 36744-Scientific misconduct check.pdf
Scientific Editor Work List 36744-Scientific editor work list.pdf