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1/26/2018 8:09:36 AM | Browse: 949 | Download: 1232
Publication Name World Journal of Hepatology
Manuscript ID 37218
Country/Territory Switzerland
Received
2017-11-22 00:44
Peer-Review Started
To Make the First Decision
2017-12-07 00:24
Return for Revision
2017-12-07 01:56
Revised
2017-12-15 07:33
Second Decision
2017-12-28 10:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-01-09 05:57
Articles in Press
2018-01-09 05:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-01-25 03:14
Publish the Manuscript Online
2018-01-26 08:09
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease
Manuscript Source Unsolicited Manuscript
All Author List Sophie Restellini, Nicolas Goossens, Sophie Clement, Nicolas Lanthier, Francesco Negro, Laura Rubbia-Brandt and Laurent Spahr
ORCID
Author(s) ORCID Number
Sophie Restellini http://orcid.org/0000-0003-0646-3439
Nicolas Goossens http://orcid.org/0000-0002-8698-4690
Sophie Clement http://orcid.org/0000-0003-1348-4887
Nicolas Lanthier http://orcid.org/0000-0002-7651-9314
Francesco Negro http://orcid.org/0000-0003-4046-4806
Laura Rubbia-Brandt http://orcid.org/0000-0002-3173-3376
Laurent Spahr http://orcid.org/0000-0001-8407-2463
Funding Agency and Grant Number
Corresponding Author Laurent Spahr, MD, Professor, Division of Gastroenterology and Hepatology, University Hospitals of Geneva, 4, Rue Gabrielle Perret Gentil, Geneva 1211, Switzerland. laurent.spahr@hcuge.ch
Key Words Fibrosis; Hepatic venous pressure gradient; Cirrhosis; Chronic advanced liver disease; Collagen proportionate area
Core Tip This is the first study exploring the relationships between fibrosis density assessed by collagen proportionate area (CPA) in liver biopsy, hepatic venous pressure gradient (HVPG) and development of clinical manifestations of portal hypertension in patients with chronic advanced alcoholic liver disease addressed for liver investigations. The results suggest a positive correlation between high fibrosis density and the HVPG only in active drinkers. HVPG, but not CPA, predicts clinical events in active alcohol drinkers pointing to the role of alcohol as a modulator of portal hypertension.
Publish Date 2018-01-26 08:09
Citation Restellini S, Goossens N, Clément S, Lanthier N, Negro F, Rubbia-Brandt L, Spahr L. Collagen proportionate area correlates to hepatic venous pressure gradient in non-abstinent cirrhotic patients with alcoholic liver disease. World J Hepatol 2018; 10(1): 73-81
URL http://www.wjgnet.com/1948-5182/full/v10/i1/73.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i1.73
Full Article (PDF) WJH-10-73.pdf
Full Article (Word) WJH-10-73.doc
Manuscript File 37218-Review.docx
Answering Reviewers 37218-Answering reviewers.pdf
Audio Core Tip 37218-Audio core tip.mp3
Biostatistics Review Certificate 37218-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37218-Conflict-of-interest statement.pdf
Copyright License Agreement 37218-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 37218-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 37218-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37218-Non-Native Speakers of English Editing Certificate.docx
Supplementary Material 37218-Supplementary material.pdf
Peer-review Report 37218-Peer-review(s).pdf
Scientific Misconduct Check 37218-Scientific misconduct check.pdf
Scientific Editor Work List 37218-Scientific editor work list.pdf