BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
3/4/2018 12:36:47 PM | Browse: 819 | Download: 990
Publication Name World Journal of Hepatology
Manuscript ID 37331
Country/Territory Pakistan
Received
2017-12-05 09:49
Peer-Review Started
2017-12-05 23:10
To Make the First Decision
2018-01-15 03:29
Return for Revision
2018-01-15 07:57
Revised
2018-02-06 22:19
Second Decision
2018-02-08 08:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-02-09 03:03
Articles in Press
2018-02-09 03:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-02-26 10:21
Publish the Manuscript Online
2018-03-04 12:36
ISSN 1948-5182 (online)
Open Access Open-Access: This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Impact of direct acting antivirals on occurrence and recurrence of hepatocellular carcinoma: Biologically plausible or an epiphenomenon?
Manuscript Source Invited Manuscript
All Author List Amna Subhan Butt, Fatima Sharif and Shahab Abid
ORCID
Author(s) ORCID Number
Amna Subhan Butt http://orcid.org/0000-0002-7311-4055
Fatima Sharif http://orcid.org/0000-0002-3366-9830
Shahab Abid http://orcid.org/0000-0003-2520-0378
Funding Agency and Grant Number
Corresponding Author Shahab Abid, FACG, FCPS, MD, PhD, Professor, Section of Gastroenterology at Department of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan. shahab.abid@aku.edu
Key Words Hepatocellular carcinoma; Direct acting antivirals; Hepatitis C
Core Tip The ground-breaking discovery of the new group of direct acting antiviral agents (DAAs) had led to a paradigm shift in the management of chronic hepatitis C (CHC). Wide variations have been observed in the studies assessing the long-term role of DAA based therapy on occurrence and recurrence of HCC. There is a need to differentiate weather the reported higher occurrence recurrence rates are due to DAA or host and disease related factors and to identify subset of individuals particularly at risk. Also, future investigations should be directed towards assessing the long-term effects of DAAs on group of patients that have not been studied thus far. Some important Centers in Europe and United States have been delaying antiviral treatment for 6 mo or more after the recent treatment for HCC. Hence, until more robust data is available, clinical practices should continue as per current guidelines in those patient groups who can benefit from DAA therapy with close surveillance of patients with advance fibrosis. Our aim is to consolidate the existing literature as well as to identify whether there is a particular subset of the population in which this phenomenon was witnessed.
Publish Date 2018-03-04 12:36
Citation Butt AS, Sharif F, Abid S. Impact of direct acting antivirals on occurrence and recurrence of hepatocellular carcinoma: Biologically plausible or an epiphenomenon? World J Hepatol 2018; 10(2): 267-276
URL http://www.wjgnet.com/1948-5182/full/v10/i2/267.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i2.267
Full Article (PDF) WJH-10-267.pdf
Full Article (Word) WJH-10-267.doc
Manuscript File 37331-Review.docx
Answering Reviewers 37331-Answering reviewers.pdf
Audio Core Tip 37331-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 37331-Conflict-of-interest statement.pdf
Copyright License Agreement 37331-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 37331-Language certificate.pdf
Peer-review Report 37331-Peer-review(s).pdf
Scientific Misconduct Check 37331-Scientific misconduct check.pdf
Scientific Editor Work List 37331-Scientific editor work list.pdf