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3/5/2018 11:23:39 AM | Browse: 1080 | Download: 1350
Publication Name World Journal of Gastroenterology
Manuscript ID 37541
Country/Territory Ireland
Received
2018-01-10 15:39
Peer-Review Started
2018-01-10 18:41
To Make the First Decision
2018-01-17 01:32
Return for Revision
2018-01-18 06:02
Revised
2018-02-05 14:24
Second Decision
2018-02-08 05:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-02-09 05:35
Articles in Press
2018-02-09 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-03-03 07:06
Publish the Manuscript Online
2018-03-05 11:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?
Manuscript Source Invited Manuscript
All Author List Denise E Brennan, Colin Dowd, Colm O'Morain, Deirdre McNamara and Sinead M Smith
ORCID
Author(s) ORCID Number
Denise E Brennan http://orcid.org/0000-0001-8200-3181
Colin Dowd http://orcid.org/0000-0003-0608-0585
Colm O'Morain http://orcid.org/0000-0002-1847-6782
Deirdre McNamara http://orcid.org/0000-0003-2324-3382
Sinead M Smith http://orcid.org/0000-0003-3460-3590
Funding Agency and Grant Number
Funding Agency Grant Number
the Health Research Board HRA-POR-2014-526
Corresponding Author Sinead M Smith, PhD, Assistant Professor, Department of Clinical Medicine, Trinity College Dublin, Trinity Centre Tallaght Hospital, Dublin D24, Ireland. smithsi@tcd.ie
Key Words Helicobacter pylori; Antibiotic resistance; Fluoroquinolone; Clarithromycin; Virulence factor; VacA; CagA
Core Tip The management of Helicobacter pylori (H. pylori) infection is challenging, largely due to the emergence of antibiotic resistance. A greater under­standing of local antibiotic resistance rates is important in determining the most appropriate treatment regimen in a given population. Furthermore, insight into the virulence of the infecting strains and the association between virulence and antibiotic resistance could potentially be an avenue to explore in the effort to improve eradication rates. This study provides and update on the prevalence of clarithromycin and flu­oroquinolone resistance in Ireland and demonstrates that less virulent strains of H. pylori are predictive of primary clarithromycin resistance.
Publish Date 2018-03-05 11:23
Citation Brennan DE, Dowd C, O’Morain C, McNamara D, Smith SM. Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection? World J Gastroenterol 2018; 24(9): 971-981
URL http://www.wjgnet.com/1007-9327/full/v24/i9/971.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i9.971
Full Article (PDF) WJG-24-971.pdf
Full Article (Word) WJG-24-971.doc
The ARRIVE Guidelines 37541-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 37541-Review.docx
Answering Reviewers 37541-Answering reviewers.pdf
Audio Core Tip 37541-Audio core tip.mp3
Biostatistics Review Certificate 37541-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 37541-Conflict-of-interest statement.pdf
Copyright License Agreement 37541-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 37541-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 37541-Institutional-Animal-Care-and-Use-Committee-Approval-Form-or-Document-revision.pdf
Institutional Review Board Approval Form or Document 37541-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 37541-Language certificate.pdf
Peer-review Report 37541-Peer-review(s).pdf
Scientific Misconduct Check 37541-Scientific misconduct check.pdf
Scientific Editor Work List 37541-Scientific editor work list.pdf