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3/26/2018 8:48:04 AM | Browse: 729 | Download: 854
Publication Name World Journal of Gastroenterology
Manuscript ID 38317
Country/Territory Japan
2018-02-13 13:08
Peer-Review Started
2018-02-13 19:26
To Make the First Decision
2018-02-24 01:54
Return for Revision
2018-02-27 02:04
2018-03-05 03:19
Second Decision
2018-03-06 10:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-06 17:00
Articles in Press
2018-03-06 17:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-03-23 09:03
Publish the Manuscript Online
2018-03-26 08:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Intraoperative frozen section diagnosis of bile duct margin for extrahepatic cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Takayuki Shiraki, Hajime Kuroda, Atsuko Takada, Yoshimasa Nakazato, Keiichi Kubota and Yasuo Imai
Author(s) ORCID Number
Takayuki Shiraki http://orcid.org/0000-0003-2935-6708
Hajime Kuroda http://orcid.org/0000-0001-6546-5317
Atsuko Takada http://orcid.org/0000-0001-7042-435X
Yoshimasa Nakazato http://orcid.org/0000-0002-0325-9451
Keiichi Kubota http://orcid.org/0000-0003-4484-7708
Yasuo Imai http://orcid.org/0000-0002-1422-7789
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Education, Culture, Sports, Science and Technology of Japan JP16K08695
Corresponding Author Yasuo Imai, MD, PhD, Professor, Department of Diagnostic Pathology, Dokkyo Med Univ, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321-0293, Japan. ya-imai@dokkyomed.ac.jp
Key Words Cholangiocarcinoma; Bile duct cancer; Frozen section diagnosis; Permanent section diagnosis; Bile duct margin; Biliary intraepithelial neoplasia; Dysplasia; Indefinite for neoplasia; Borderline lesion; Local recurrence
Core Tip Usefulness of intraoperative frozen section diagnosis (FSD) of bile duct margin for extrahepatic cholangiocarcinoma was investigated. The diagnosis was classified into negative, borderline (biliary in­traepithelial neoplasia-1 and 2, and indefinite for neoplasia), or positive, and FSD was compared with permanent section diagnosis postoperatively. In contrast to previous studies, positive FSD in the epithelial layer was significantly associated with local recurrence. Furthermore, borderline FSD in the epithelial layer could be substantially regarded as negative, which could aid surgeons to determine the resection range of the bile duct. Finally, we demonstrated that FSD was reliable enough for pathological diagnosis.
Publish Date 2018-03-26 08:48
Citation Shiraki T, Kuroda H, Takada A, Nakazato Y, Kubota K, Imai Y. Intraoperative frozen section diagnosis of bile duct margin for extrahepatic cholangiocarcinoma. World J Gastroenterol 2018; 24(12): 1332-1342
URL http://www.wjgnet.com/1007-9327/full/v24/i12/1332.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i12.1332
Full Article (PDF) WJG-24-1332.pdf
Full Article (Word) WJG-24-1332.doc
Manuscript File 38317-Review.docx
Answering Reviewers 38317-Answering reviewers.pdf
Audio Core Tip 38317-Audio core tip.MP3
Conflict-of-Interest Disclosure Form 38317-Conflict-of-interest statement.pdf
Copyright License Agreement 38317-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 38317-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 38317-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 38317-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 38317-Language certificate.pdf
Peer-review Report 38317-Peer-review(s).pdf
Scientific Misconduct Check 38317-Scientific misconduct check.pdf
Scientific Editor Work List 38317-Scientific editor work list.pdf