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3/23/2018 1:28:41 PM | Browse: 944 | Download: 846
Publication Name World Journal of Stem Cells
Manuscript ID 38393
Country Italy
Received
2018-02-19 14:39
Peer-Review Started
2018-02-19 17:38
To Make the First Decision
2018-03-13 00:12
Return for Revision
2018-03-13 03:00
Revised
2018-03-20 13:17
Second Decision
2018-03-21 08:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-03-21 17:41
Articles in Press
2018-03-21 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-03-22 11:12
Publish the Manuscript Online
2018-03-23 13:28
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells
Manuscript Source Invited Manuscript
All Author List Adriana Carol Eleonora Graziano, Rosanna Avola, Vincenzo Perciavalle, Ferdinando Nicoletti, Gianluca Cicala, Marinella Coco and Venera Cardile
ORCID
Author(s) ORCID Number
Adriana Carol Eleonora Graziano http://orcid.org/0000-0003-1652-9577
Rosanna Avola http://orcid.org/0000-0002-3094-2416
Vincenzo Perciavalle http://orcid.org/0000-0003-0614-2969
Ferdinando Nicoletti http://orcid.org/0000-0002-4570-8462
Gianluca Cicala http://orcid.org/0000-0002-4680-152X
Marinella Coco http://orcid.org/0000-0002-1797-2717
Venera Cardile http://orcid.org/0000-0001-9902-3736
Funding Agency and Grant Number
Funding Agency Grant Number
university of Catania - FIR2014 21040104
Corresponding Author Adriana Carol Eleonora Graziano, PharmD, PhD, Research Fellow, Department of Biomedical and Biotechnological Sciences, Section of Physiology, University of Catania, Via Santa Sofia 97, Catania 95123, Italy. acegraz@unict.it
Key Words Adipose stem cells; Biomaterials; Neurodegeneration; Neural differentiation; Physiological microenvironment
Core Tip Adipose-derived stem cells are easily accessible from liposuction, obtained in large quantity and cultured for several months with low levels of senescence. Moreover, they could be induced toward a neural phenotype in vitro. The preclinical studies show that microenvironment has a predominant role. Our objective is to consolidate the current literature to better delineate the functional response of adipose-derived stem cells to biochemical, biophysical or dimensional stimuli. Specifically, chemicals - like drugs and growth factors-biomaterials and microgravity are here discussed as both single and co-applied parameters for inducing a neural lineage.
Publish Date 2018-03-23 13:28
Citation Graziano ACE, Avola R, Perciavalle V, Nicoletti F, Cicala G, Coco M, Cardile V. Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells. World J Stem Cells 2018; 10(3): 23-33
URL http://www.wjgnet.com/1948-0210/full/v10/i3/23.htm
DOI http://dx.doi.org/10.4252/wjsc.v10.i3.23
Full Article (PDF) WJSC-10-23.pdf
Full Article (Word) WJSC-10-23.doc
Manuscript File 38393-Review.docx
Answering Reviewers 38393-Answering reviewers.pdf
Audio Core Tip 38393-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 38393-Conflict-of-interest statement.pdf
Copyright License Agreement 38393-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 38393-Grant application form(s).pdf
Peer-review Report 38393-Peer-review(s).pdf
Scientific Misconduct Check 38393-Scientific misconduct check.pdf
Scientific Editor Work List 38393-Scientific editor work list.pdf