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9/27/2018 9:38:46 AM | Browse: 760 | Download: 882
Publication Name World Journal of Hepatology
Manuscript ID 38812
Country/Territory China
Received
2018-03-20 02:55
Peer-Review Started
2018-03-20 07:25
To Make the First Decision
2018-04-13 03:19
Return for Revision
2018-04-18 11:11
Revised
2018-07-10 10:00
Second Decision
2018-07-13 08:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-07-16 05:28
Articles in Press
2018-07-16 05:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-07-27 01:55
Typeset the Manuscript
2018-09-20 01:42
Publish the Manuscript Online
2018-09-27 09:38
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Progression and status of antiviral monitoring in patients with chronic hepatitis B: From HBsAg to HBV RNA
Manuscript Source Invited Manuscript
All Author List Ya-Yun Liu and Xue-Song Liang
ORCID
Author(s) ORCID Number
Ya-Yun Liu http://orcid.org/0000-0002-4530-1873
Xue-Song Liang http://orcid.org/0000-0003-0527-4978
Funding Agency and Grant Number
Corresponding Author Xue-Song Liang, MD, PhD, Associate Professor, Department of Infectious Diseases, Changhai Hospital of Second Military Medical University, Changhai Road 168#, Shanghai 200433, China. liangxuesong2000@163.com
Key Words Hepatitis B core-related antigen; Response prediction; Chronic hepatitis B; Interferon; Nucleos(t)ide analogs; Hepatitis B surface antigen; Progenome RNA
Core Tip As the surrogate biomarkers of intrahepatic viral replicative activity, hepatitis B surface antigen (HBsAg), hepatitis B core-related antigen (HbcrAg), and serum hepatitis B virus (HBV) RNA levels have been advocated as novel serum markers for treatment response in chronic hepatitis B. Currently, quantitative HBsAg has been widely used for predicting treatment response of chronic hepatitis B. HBcrAg can predict the risk of post-treatment reactivation of HBV as it is detectable in patients whose HBV DNA levels are undetectable or HBsAg loss is achieved. Serum HBV RNA may be useful in monitoring drug withdrawal, but clinical studies with large sample sizes remain necessary to further determine this capability.
Publish Date 2018-09-27 09:38
Citation Liu YY, Liang XS. Progression and status of antiviral monitoring in patients with chronic hepatitis B: From HBsAg to HBV RNA. World J Hepatol 2018; 10(9): 603-611
URL http://www.wjgnet.com/1948-5182/full/v10/i9/603.htm
DOI http://dx.doi.org/10.4254/wjh.v10.i9.603
Full Article (PDF) WJH-10-603.pdf
Full Article (Word) WJH-10-603.doc
Manuscript File 38812-Review.docx
Answering Reviewers 38812-Answering reviewers.pdf
Audio Core Tip 38812-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 38812-Conflict-of-interest statement.pdf
Copyright License Agreement 38812-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 38812-Language certificate.pdf
Peer-review Report 38812-Peer-review(s).pdf
Scientific Misconduct Check 38812-Scientific misconduct check.pdf
Scientific Editor Work List 38812-Scientific editor work list.pdf