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7/19/2018 7:04:34 AM | Browse: 977 | Download: 1453
Publication Name World Journal of Gastroenterology
Manuscript ID 39524
Country/Territory Italy
Received
2018-04-28 07:43
Peer-Review Started
2018-04-28 14:39
To Make the First Decision
2018-05-30 00:23
Return for Revision
2018-06-11 08:38
Revised
2018-06-12 19:35
Second Decision
2018-06-27 09:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-27 17:26
Articles in Press
2018-06-27 17:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-07-02 21:03
Typeset the Manuscript
2018-07-18 02:48
Publish the Manuscript Online
2018-07-19 07:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Clinical Trials Study
Article Title New fecal test for non-invasive Helicobacter pylori detection: A diagnostic accuracy study
Manuscript Source Invited Manuscript
All Author List Andrea Iannone, Floriana Giorgio, Francesco Russo, Giuseppe Riezzo, Bruna Girardi, Maria Pricci, Suetonia C Palmer, Michele Barone, Mariabeatrice Principi, Giovanni FM Strippoli, Alfredo Di Leo and Enzo Ierardi
ORCID
Author(s) ORCID Number
Andrea Iannone http://orcid.org/0000-0002-5468-9515
Floriana Giorgio http://orcid.org/0000-0001-5209-1256
Francesco Russo http://orcid.org/0000-0003-0538-6072
Giuseppe Riezzo http://orcid.org/0000-0002-1800-4830
Bruna Girardi http://orcid.org/0000-0003-3848-7996
Maria Pricci http://orcid.org/0000-0002-2158-6392
Suetonia C Palmer http://orcid.org/0000-0001-7765-5871
Michele Barone http://orcid.org/0000-0001-8284-5127
Mariabeatrice Principi http://orcid.org/0000-0003-0545-5656
Giovanni FM Strippoli http://orcid.org/0000-0002-6936-0616
Alfredo Di Leo http://orcid.org/0000-0003-2026-1200
Enzo Ierardi http://orcid.org/0000-0001-7275-5080
Funding Agency and Grant Number
Corresponding Author Enzo Ierardi, MD, Associate Professor, Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Piazza Giulio Cesare 11, Bari 70124, Italy. e.ierardi@virgilio.it
Key Words Helicobacter pylori; Fecal test; Feces; Stools; 23S rRNA; Molecular analysis; Antibiotic resistance; Diagnostic accuracy
Core Tip Existing studies on molecular tests for Helicobacter pylori (H. pylori) detection in stools show suboptimal quality. The THD fecal test is a newer method to detect bacterial DNA and mutations conferring antibiotic resistance. In this diagnostic test accuracy study involving unselected consecutive participants and blinded outcome assessment, we evaluated the diagnostic accuracy of the THD fecal test for detecting H. pylori, using the 13C-urea breath test as the reference standard. We found that the THD fecal test has high performance for the non-invasive diagnosis of H. pylori infection while additionally enabling the assessment of bacterial antibiotic resistances.
Publish Date 2018-07-19 07:04
Citation Iannone A, Giorgio F, Russo F, Riezzo G, Girardi B, Pricci M, Palmer SC, Barone M, Principi M, Strippoli GF, Di Leo A, Ierardi E. New fecal test for non-invasive Helicobacter pylori detection: A diagnostic accuracy study. World J Gastroenterol 2018; 24(27): 3021-3029
URL http://www.wjgnet.com/1007-9327/full/v24/i27/3021.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i27.3021
Full Article (PDF) WJG-24-3021.pdf
Full Article (Word) WJG-24-3021.doc
Manuscript File 39524-Review.docx
Answering Reviewers 39524-Answering reviewers.pdf
Audio Core Tip 39524-Audio core tip.mp3
Biostatistics Review Certificate 39524-Biostatistics statement.pdf
Clinical Trial Registration Statement 39524-Clinical Trial Registration Statement.pdf
Conflict-of-Interest Disclosure Form 39524-Conflict-of-interest statement.pdf
Copyright License Agreement 39524-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 39524-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 39524-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 39524-Language certificate.pdf
Supplementary Material 39524-Supplementary material.pdf
Peer-review Report 39524-Peer-review(s).pdf
Scientific Misconduct Check 39524-Scientific misconduct check.pdf
Scientific Editor Work List 39524-Scientific editor work list.pdf