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6/21/2018 12:52:29 AM | Browse: 957 | Download: 1527
Publication Name World Journal of Clinical Cases
Manuscript ID 39532
Country/Territory Thailand
Received
2018-04-27 01:17
Peer-Review Started
2018-04-27 01:47
To Make the First Decision
2018-05-09 00:30
Return for Revision
2018-05-09 02:37
Revised
2018-05-11 07:34
Second Decision
2018-05-30 13:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-05-31 04:37
Articles in Press
2018-05-31 04:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-06-07 04:12
Publish the Manuscript Online
2018-06-21 00:52
ISSN 2307-8960 (online)
Open Access This article is an open access article, which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creative commons.org/licenses/by-nc/4.0
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Retrospective Study
Article Title Prognostic role of alpha-fetoprotein response after hepatocellular carcinoma resection
Manuscript Source Invited Manuscript
All Author List Narongsak Rungsakulkij, Wikran Suragul, Somkit Mingphruedhi, Pongsatorn Tangtawee, Paramin Muangkaew and Suraida Aeesoa
ORCID
Author(s) ORCID Number
Narongsak Rungsakulkij http://orcid.org/0000-0003-3522-5800
Wikran Suragul http://orcid.org/0000-0002-9933-9279
Somkit Mingphruedhi http://orcid.org/0000-0002-1404-1968
Pongsatorn Tangtawee http://orcid.org/0000-0001-9598-5479
Paramin Muangkaew http://orcid.org/0000-0002-2470-8164
Suraida Aeesoa http://orcid.org/0000-0002-4137-3861
Funding Agency and Grant Number
Corresponding Author Wikran Suragul, FRCS (Gen Surg), MD, Doctor, Surgeon, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Praram VI Road, Ratchathewi, Bangkok 10400, Thailand. wikran.sur@mahidol.ac.th
Key Words Risk factors; Prognosis; Alpha-fetoprotein; Hepatocellular carcinoma; Liver neoplasms
Core Tip Alpha-fetoprotein (AFP) is a widely used tumor marker for both pre- and post-treatment hep­atocellular carcinoma (HCC) patients. To investigate whether changes in pre- and post-operation serum AFP levels were a predictive prognostic factor in HCC patients, we retrospectively analyzed 334 HCC patients who underwent hepatic resection at our hospital. Serum AFP responses were found to be a significant prognostic factor for surgical outcomes in patients with high pre-operative AFP levels. The non-response group, which was classified as having a < 50% decrease from preoperative AFP levels that were > 20 ng/mL, was associated with poor outcomes. In summary, post-surgery AFP levels are valuable for properly managing HCC patients.
Publish Date 2018-06-21 00:52
Citation Rungsakulkij N, Suragul W, Mingphruedhi S, Tangtawee P, Muangkaew P, Aeesoa S. Prognostic role of alpha-fetoprotein response after hepatocellular carcinoma resection. World J Clin Cases 2018; 6(6): 110-120
URL http://www.wjgnet.com/2307-8960/full/v6/i6/110.htm
DOI http://dx.doi.org/10.12998/wjcc.v6.i6.110
Full Article (PDF) WJCC-6-110.pdf
Full Article (Word) WJCC-6-110.doc
Manuscript File 39532-Review.docx
Answering Reviewers 39532-Answering reviewers.pdf
Audio Core Tip 39532-Audio core tip.MP3
Biostatistics Review Certificate 39532-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 39532-Conflict-of-interest statement.pdf
Copyright License Agreement 39532-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 39532-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 39532-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 39532-Language certificate.pdf
Peer-review Report 39532-Peer-review(s).pdf
Scientific Misconduct Check 39532-Scientific misconduct check.pdf
Scientific Editor Work List 39532-Scientific editor work list.pdf