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Articles Published Processes
8/27/2018 7:22:43 AM | Browse: 850 | Download: 987
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Received |
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2018-05-18 09:30 |
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Peer-Review Started |
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2018-05-19 13:35 |
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To Make the First Decision |
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2018-06-06 02:20 |
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Return for Revision |
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2018-06-11 08:52 |
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Revised |
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2018-06-14 22:52 |
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Second Decision |
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2018-06-26 11:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-06-27 04:03 |
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Articles in Press |
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2018-06-27 04:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-03 01:19 |
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Typeset the Manuscript |
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2018-08-27 01:40 |
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Publish the Manuscript Online |
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2018-08-27 07:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Abnormal expression of HMGB-3 is significantly associated with malignant transformation of hepatocytes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Jie Zheng, Min Yao, Miao Fang, Li Wang, Zhi-Zhen Dong and Deng-Fu Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81673241 |
| National Natural Science Foundation of China |
81702419 |
| Projects of Jiangsu Medical Science |
BE2016698 |
| Jiangsu Graduate Innovation |
KYCX17_1934 |
| Nantong Health and Family Planning Commission |
WQ2016083 |
| National Int S&T Cooperation Program |
2013DFA32150 |
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| Corresponding Author |
Deng-Fu Yao, MD, PhD, Postdoc, Professor, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, No. 20 West Temple Road, Nantong 226001, Jiangsu, China. yaodf@ahnmc.com |
| Key Words |
Liver cancer; HMGB-3; Hepatocarcinogenesis; Proliferation; Tumor growth |
| Core Tip |
high mobility group box (HMGB) family proteins were correlated with hepatocellular carcinoma (HCC) development and progression. This current study examined the effects of HMGB3 on HCC both in vitro and in vivo. Overexpression of HMGB3 was observed in hepatic malignant transformation and HCC tissues in bioinformatic databases. Knockdown of HMGB3 significantly inhibited proliferation, cell cycle, and tumor growth of HCC cells, providing a novel insight for HCC research. |
| Publish Date |
2018-08-27 07:22 |
| Citation |
Zheng WJ, Yao M, Fang M, Wang L, Dong ZZ, Yao DF. Abnormal expression of HMGB-3 is significantly associated with malignant transformation of hepatocytes. World J Gastroenterol 2018; 24(32): 3650-3662 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i32/3650.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i32.3650 |
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