Publication Name	World Journal of Hepatology
Manuscript ID	39915
Country	United States

Received	2018-05-21 01:15
Peer-Review Started	2018-05-21 08:03
To Make the First Decision	2018-06-06 07:52
Return for Revision	2018-06-08 02:07
Revised	2018-06-25 17:02
Second Decision	2018-06-27 09:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-28 17:23
Articles in Press	2018-06-28 17:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-08-27 08:00
Publish the Manuscript Online	2018-08-27 12:43

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Current status of imaging in nonalcoholic fatty liver disease
Manuscript Source	Unsolicited Manuscript
All Author List	Qian Li, Manish Dhyani, Joseph R Grajo, Claude Sirlin and Anthony E Samir
ORCID	Author(s) ORCID Number Qian Li http://orcid.org/0000-0001-8827-939X Manish Dhyani http://orcid.org/0000-0002-2651-1859 Joseph R Grajo http://orcid.org/0000-0002-9704-2447 Claude Sirlin http://orcid.org/0000-0002-6639-9072 Anthony E Samir http://orcid.org/0000-0002-7801-8724
Funding Agency and Grant Number	Funding Agency Grant Number NIBIB of the National Institutes of Health (to Samir C) K23 EB020710
Corresponding Author	Manish Dhyani, MD, Research Associate, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White 270, Boston, MA 02114, United States. manishdhyani@icloud.com
Key Words	Simple steatosis; Non-alcoholic fatty liver disease; Ultrasonography; Computed tomography; Nonalcoholic steatohepatitis; Elastography; Magnetic resonance
Core Tip	Patients with non-alcoholic fatty liver disease (NAFLD) are at risk of steatohepatitis and progressive liver fibrosis culminating in cirrhosis, typically over a period of decades. Early diagnosis and risk stratification are essential for effective management. Current imaging methods such as ultrasound, computed tomography, and magnetic resonance elastography have demonstrated their values to serve as noninvasive imaging biomarkers to evaluate NAFLD progression, but they are still relatively limited in the detection of inflammation, which is more important than steatosis in terms of its high risk for fibrosis, cirrhosis, and hepatocellular carcinoma.
Publish Date	2018-08-27 12:43
Citation	Li Q, Dhyani M, Grajo JR, Sirlin C, Samir AE. Current status of imaging in nonalcoholic fatty liver disease. World J Hepatol 2018; 10(8): 530-542
URL	http://www.wjgnet.com/1948-5182/full/v10/i8/530.htm
DOI	http://dx.doi.org/10.4254/wjh.v10.i8.530

Full Article (PDF)	WJH-10-530.pdf
Full Article (Word)	WJH-10-530.doc
Manuscript File	39915-Review.docx
Answering Reviewers	39915-Answering reviewers.pdf
Audio Core Tip	39915-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39915-Conflict-of-interest statement.pdf
Copyright License Agreement	39915-Copyright assignment.pdf
Peer-review Report	39915-Peer-review(s).pdf
Scientific Misconduct Check	39915-Scientific misconduct check.pdf
Scientific Editor Work List	39915-Scientific editor work list.pdf