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9/25/2018 3:44:36 AM | Browse: 918 | Download: 1282
Publication Name World Journal of Gastroenterology
Manuscript ID 40077
Country/Territory Austria
Received
2018-05-30 01:42
Peer-Review Started
2018-05-30 06:12
To Make the First Decision
2018-07-04 01:14
Return for Revision
2018-07-06 03:27
Revised
2018-07-11 10:48
Second Decision
2018-07-31 12:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-08-01 04:29
Articles in Press
2018-08-01 04:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-09-20 07:59
Publish the Manuscript Online
2018-09-25 03:44
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Physiology
Manuscript Type Review
Article Title Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives
Manuscript Source Invited Manuscript
All Author List Luca Iamartino, Taha Elajnaf, Enikö Kallay and Martin Schepelmann
ORCID
Author(s) ORCID Number
Luca Iamartino http://orcid.org/0000-0003-0794-3565
Taha Elajnaf http://orcid.org/0000-0002-7293-254X
Enikö Kallay http://orcid.org/0000-0002-4996-0104
Martin Schepelmann http://orcid.org/0000-0002-7017-5426
Funding Agency and Grant Number
Funding Agency Grant Number
EU Horizon 2020 Research and Innovation 675228
Austrian Science Fund (FWF) P 29948-B28
Corresponding Author Martin Schepelmann, PhD, Postdoctoral Fellow, Department of Pathophysiology and Allergy Research, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria. martin.schepelmann@meduniwien.ac.at
Key Words Calcium-sensing receptor; Colon; Cancer; Inflammation; Calcimimetics; Calcilytics
Core Tip The extracellular calcium-sensing receptor (CaSR) is best known for its roles in maintaining body calcium homeostasis, but it is also expressed in the intestines where it is assumed to be involved in pathologies such as inflammatory bowel disease and colorectal cancer. It has been suggested to act as a tumour suppressor in colorectal tumourigenesis. In this review we highlight the evidence for the anti-inflammatory and anti-tumourigenic roles of the CaSR, its signalling pathways, and its potential for future use as a drug target in the context of inflammatory bowel disease and colorectal cancer.
Publish Date 2018-09-25 03:44
Citation Iamartino L, Elajnaf T, Kallay E, Schepelmann M. Calcium-sensing receptor in colorectal inflammation and cancer: Current insights and future perspectives. World J Gastroenterol 2018; 24(36): 4119-4131
URL http://www.wjgnet.com/1007-9327/full/v24/i36/4119.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i36.4119
Full Article (PDF) WJG-24-4119.pdf
Full Article (Word) WJG-24-4119.doc
Manuscript File 40077-Review.docx
Answering Reviewers 40077-Answering reviewers.pdf
Audio Core Tip 40077-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 40077-Conflict-of-interest statement.pdf
Copyright License Agreement 40077-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 40077-Grant application form(s).pdf
Peer-review Report 40077-Peer-review(s).pdf
Scientific Misconduct Check 40077-Scientific misconduct check.pdf
Scientific Editor Work List 40077-Scientific editor work list.pdf