| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic value of vascular endothelial growth factor receptor 1 and class III β-tubulin in survival for non-metastatic rectal cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiang-Quan Kong, Yun-Xia Huang, Jin-Luan Li, Xue-Qing Zhang, Qing-Qin Peng, Li-Rui Tang and Jun-Xin Wu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fujian Province Natural Science Foundation |
2016J01437 |
|
2017J01260 |
|
2018J01266 |
| Fujian Medical Innovation Project |
2015-CX-8 |
| Peking University Cancer Hospital and Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing (2017 Open Project-9), Joint Funds for the innovation of science and Technology, Fujian Province |
2017Y9074 |
|
| Corresponding Author |
Jun-Xin Wu, PhD, Attending Doctor, Professor, Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, 420 Fuma Rd, Jinan District, Fuzhou 350014, Fujian Province, China. junxinwufj@aliyun.com |
| Key Words |
Rectal cancer; Class Ⅲ β-tubulin; Vascular endothelial growth factor receptor 1; Overall survival |
| Core Tip |
Nowadays, personalized and precision medicine becomes vital in cancer treatment. Herein, we focus on the long-term prognostic value of vascular endothelial growth factor receptor 1 (VEGFR1) and class Ⅲ β-tubulin (TUBB3) mRNA expression in non-metastatic rectal cancer. In the 75 consecutive patients enrolled, we found that VEGFR1 expression and lymph node metastasis were independent factors influencing overall survival, and the combination of them showed a favorable prognostic value. Also, VEGFR1 expression was significantly related to lymph node metastasis. In addition, VEGFR1 expression was positively correlated with TUBB3 expression. |
| Publish Date |
2018-10-15 12:09 |
| Citation |
Kong XQ, Huang YX, Li JL, Zhang XQ, Peng QQ, Tang LR, Wu JX. Prognostic value of vascular endothelial growth factor receptor 1 and class III β-tubulin in survival for non-metastatic rectal cancer. World J Gastrointest Oncol 2018; 10(10): 351-359 |
| URL |
http://www.wjgnet.com/1948-5204/full/v10/i10/351.htm |
| DOI |
http://dx.doi.org/10.4251/wjgo.v10.i10.351 |
