Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	40218
Country	Italy

Received	2018-06-09 08:32
Peer-Review Started	2018-06-09 10:23
To Make the First Decision	2018-07-12 00:24
Return for Revision	2018-07-13 01:59
Revised	2018-08-05 15:51
Second Decision	2018-08-18 04:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-08-21 22:28
Articles in Press	2018-08-21 22:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-09-01 00:42
Typeset the Manuscript	2018-10-08 13:18
Publish the Manuscript Online	2018-10-15 12:09

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases
Manuscript Source	Invited Manuscript
All Author List	Emilio De Raffele, Mariateresa Mirarchi, Dajana Cuicchi, Ferdinando Lecce, Claudio Ricci, Riccardo Casadei, Bruno Cola and Francesco Minni
ORCID	Author(s) ORCID Number Emilio De Raffele http://orcid.org/0000-0003-1743-7471 Mariateresa Mirarchi http://orcid.org/0000-0003-1896-2438 Dajana Cuicchi http://orcid.org/0000-0002-1504-4888 Ferdinando Lecce http://orcid.org/0000-0003-2042-0339 Claudio Ricci http://orcid.org/0000-0001-5566-8444 Riccardo Casadei http://orcid.org/0000-0002-4044-3557 Bruno Cola http://orcid.org/0000-0002-3568-9835 Francesco Minni http://orcid.org/0000-0002-9679-8971
Funding Agency and Grant Number
Corresponding Author	Emilio De Raffele, MD, PhD, Surgeon, Surgical Oncologist, Unità Operativa di Chirurgia Generale, Dipartimento dell'Apparato Digerente, Azienda Ospedaliero-Universitaria di Bologna, Policlinico S.Orsola-Malpighi, Via Massarenti 9, Bologna 40138, Italy. e.deraffele@gmail.com
Key Words	Colorectal surgery; Synchronous colorectal liver metastases; Major hepatectomy; Parenchymal-sparing hepatectomy; Intraoperative ultrasonography; Simultaneous colorectal and liver surgery; Synchronous colorectal carcinoma; Ablative therapies
Core Tip	Simultaneous colorectal and liver resection represents an appealing surgical strategy in selected patients with colorectal cancer and resectable synch­ronous liver metastases (CRLM). Synchronous colorectal carcinoma may represent an adequate indication to simultaneous resections, even though it may require more complex colorectal resections. In patients with mul­tiple bilobar synchronous CRLM, major hepatectomies performed simultaneously with colorectal surgery have been associated with increased perioperative risks com­pared to major hepatectomies alone. Conservative or parenchymal-sparing hepatectomies reduce the extent of hepatectomy while preserving oncological radicality, and may represent the best option to reduce the periopera­tive risks of simultaneous colorectal and liver resection.
Publish Date	2018-10-15 12:09
Citation	De Raffele E, Mirarchi M, Cuicchi D, Lecce F, Ricci C, Casadei R, Cola B, Minni F. Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases. World J Gastrointest Oncol 2018; 10(10): 293-316
URL	http://www.wjgnet.com/1948-5204/full/v10/i10/293.htm
DOI	http://dx.doi.org/10.4251/wjgo.v10.i10.293

Full Article (PDF)	WJGO-10-293.pdf
Full Article (Word)	WJGO-10-293.doc
Manuscript File	40218-Review.doc
Answering Reviewers	40218-Answering reviewers.pdf
Audio Core Tip	40218-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	40218-Conflict-of-interest statement.pdf
Copyright License Agreement	40218-Copyright license agreement.pdf
Peer-review Report	40218-Peer-review(s).pdf
Scientific Misconduct Check	40218-Scientific misconduct check.pdf
Scientific Editor Work List	40218-Scientific editor work list.pdf