Publication Name	World Journal of Gastroenterology
Manuscript ID	41200
Country	Romania

Received	2018-07-27 12:43
Peer-Review Started	2018-07-28 09:49
To Make the First Decision	2018-08-27 00:58
Return for Revision	2018-08-27 12:12
Revised	2018-09-02 14:02
Second Decision	2018-09-13 07:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-10-05 23:06
Articles in Press	2018-10-05 23:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-18 03:03
Publish the Manuscript Online	2018-10-18 10:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Portal vein thrombosis in cirrhotic patients - it is always the small pieces that make the big picture
Manuscript Source	Invited Manuscript
All Author List	Irina Girleanu, Anca Trifan, Carol Stanciu and Catalin Sfarti
ORCID	Author(s) ORCID Number Irina Girleanu http://orcid.org/0000-0001-5925-1232 Anca Trifan http://orcid.org/0000-0001-9144-5520 Carol Stanciu http://orcid.org/0000-0002-6427-4049 Catalin Sfarti http://orcid.org/0000-0001-7074-5938
Funding Agency and Grant Number
Corresponding Author	Anca Trifan, MD, Doctor, Professor, Department of Gastroenterology, “Grigore T Popa” University of Medicine and Pharmacy, 16 Universitatii St., Iasi 700115, Romania. ancatrifan@yahoo.com
Key Words	Portal vein thrombosis; Liver cirrhosis; Classification; Risk factors; Anticoagulation
Core Tip	Portal vein thrombosis is a frequent and serious complication in patients with liver cirrhosis. The new classification needs to be validated and should contain the pattern of thrombus evolution and the status of liver cirrhosis- compensated or decompensated. The two main risk factors - reduced portal flow velocity and the hypercoagulable state should be addressed more extensively in large studies, considering the stage of liver disease. The anticoagulant treatment could be considered in cirrhotics with portal vein thrombosis. The end-points of the anticoagulant treatment should consider the recanalization, decompensation, and the mortality rates.
Publish Date	2018-10-18 10:13
Citation	Gîrleanu I, Trifan A, Stanciu C, Sfarti C. Portal vein thrombosis in cirrhotic patients - it is always the small pieces that make the big picture. World J Gastroenterol 2018; 24(39): 4419-4427
URL	http://www.wjgnet.com/1007-9327/full/v24/i39/4419.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i39.4419

Full Article (PDF)	WJG-24-4419.pdf
Full Article (Word)	WJG-24-4419.doc
Manuscript File	41200-Review.doc
Answering Reviewers	41200-Answering reviewers.pdf
Audio Core Tip	41200-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	41200-Conflict-of-interest statement.pdf
Copyright License Agreement	41200-Copyright license agreement.pdf
Peer-review Report	41200-Peer-review(s).pdf
Scientific Misconduct Check	41200-Scientific misconduct check.pdf
Scientific Editor Work List	41200-Scientific editor work list.pdf