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12/14/2018 1:19:57 AM | Browse: 262 | Download: 152
Publication Name World Journal of Diabetes
Manuscript ID 41697
Country/Territory United States
2018-08-22 03:15
Peer-Review Started
2018-08-22 09:05
To Make the First Decision
2018-10-08 03:37
Return for Revision
2018-10-10 02:23
2018-10-10 15:57
Second Decision
2018-11-14 11:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-15 17:35
Articles in Press
2018-11-15 17:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-11-24 00:53
Typeset the Manuscript
2018-12-03 03:07
Publish the Manuscript Online
2018-12-14 01:19
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology and Metabolism
Manuscript Type Observational Study
Article Title Using real world data to assess cardiovascular outcomes of two antidiabetic treatment classes
Manuscript Source Unsolicited Manuscript
All Author List Manfred Paul Stapff
Author(s) ORCID Number
Manfred Paul Stapff http://orcid.org/000-0002-6127-1109
Funding Agency and Grant Number
Corresponding author Manfred Paul Stapff, MD, PhD, Chief Medical Officer, CMO, TriNetX Inc., 125 Cambridgepark Drive, Ste 500, Cambridge, MA02140, United States. manfred.stapff@trinetx.com
Keywords Sodium-glucose co-transporter-2 inhibitors; Cardiovascular events; Clinical trials; Electronic medical records; Dipeptidyl peptidase 4 inhibitors; Real world evidence; Diabetes
Core Tip Core tip: Cardiovascular advantages of sodium-glucose co-transporter-2 (SGLT2) inhibitors were shown in com­plex clinical trials or in countries with large registries. However, it was unclear whether these findings could be applied to routine medical practice in the US. This real world analysis from 46909 patients with SGLT2 inhibitors revealed a 0.63 (95%CI: 0.60-0.66) risk ra­tio of SGLT2 inhibitors compared to 189120 patients with dipeptidyl peptidase 4 inhibitors. This analysis of electronic health records could replicate the results of randomized clinical trials, which supports the usefulness of such real world studies (e.g., for long-term outcome or safety observations).
Publish Date 2018-12-14 01:19
Citation Stapff MP. Using real world data to assess cardiovascular out­comes of two antidiabetic treatment classes. World J Diabetes 2018; 9(12): 252-257
Url https://www.wjgnet.com/1948-9358/full/v9/i12/252.htm
DOI https://dx.doi.org/10.4239/wjd.v9.i12.252
Full Article (PDF) WJD-9-252.pdf
Full Article (Word) WJD-9-252.doc
Manuscript File 41697-Review.docx
Answering Reviewers 41697-Answering reviewers.pdf
Audio Core Tip 41697-Audio core tip.mp3
Biostatistics Review Certificate 41697-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 41697-Conflict-of-interest statement.pdf
Copyright License Agreement 41697-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 41697-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 41697-Institutional review board statement.pdf
Peer-review Report 41697-Peer-review(s).pdf
Scientific Misconduct Check 41697-Scientific misconduct check.pdf
Scientific Editor Work List 41697-Scientific editor work list.pdf