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Articles Published Processes
12/7/2018 3:57:11 AM | Browse: 832 | Download: 968
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Received |
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2018-09-01 03:19 |
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Peer-Review Started |
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2018-09-03 07:46 |
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To Make the First Decision |
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2018-10-11 08:43 |
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Return for Revision |
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2018-10-14 05:34 |
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Revised |
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2018-10-21 09:08 |
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Second Decision |
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2018-11-07 09:19 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-11-08 02:33 |
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Articles in Press |
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2018-11-08 02:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-12-06 03:21 |
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Publish the Manuscript Online |
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2018-12-07 03:57 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Minireviews |
Article Title |
Multidisciplinary approach for post-liver transplant recurrence of hepatocellular carcinoma: A proposed management algorithm
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Manuscript Source |
Invited Manuscript |
All Author List |
Kin Pan Au and Kenneth Siu Ho Chok |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Kenneth Siu Ho Chok, FRCS (Ed), Associate Professor, Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong , Hong Kong, China. chok6275@hku.hk |
Key Words |
Hepatocellular carcinoma; Recurrence; Liver transplantation |
Core Tip |
We propose a multi-disciplinary management algorithm for recurrent hepatocellular carcinoma after liver transplantation. The combination of a mammalian target of rapamycin inhibitor with a reduced calcineurin inhibitor can be considered. Staging is performed to differentiate between disseminated recurrence and oligo-recurrence. In patients with disseminated recurrence, sorafenib may confer survival benefits but is associated with significant toxicity. Oligo-recurrence encompasses recurrent disease that is limited in number and location so that loco-regional treatments convey disease control and survival benefits. Intra-hepatic and extra-hepatic oligo-recurrences can be managed with surgical resection, ablative therapy or regional treatments depending on the disease status. |
Publish Date |
2018-12-07 03:57 |
Citation |
Au KP, Chok KSH. Multidisciplinary approach for post-liver transplant recurrence of hepatocellular carcinoma: A proposed management algorithm. World J Gastroenterol 2018; 24(45): 5081-5094 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i45/5081.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i45.5081 |
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