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12/7/2018 3:57:11 AM | Browse: 832 | Download: 968
Publication Name World Journal of Gastroenterology
Manuscript ID 41832
Country/Territory China
Received
2018-09-01 03:19
Peer-Review Started
2018-09-03 07:46
To Make the First Decision
2018-10-11 08:43
Return for Revision
2018-10-14 05:34
Revised
2018-10-21 09:08
Second Decision
2018-11-07 09:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-08 02:33
Articles in Press
2018-11-08 02:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-12-06 03:21
Publish the Manuscript Online
2018-12-07 03:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Minireviews
Article Title Multidisciplinary approach for post-liver transplant recurrence of hepatocellular carcinoma: A proposed management algorithm
Manuscript Source Invited Manuscript
All Author List Kin Pan Au and Kenneth Siu Ho Chok
ORCID
Author(s) ORCID Number
Kin Pan Au http://orcid.org/0000-0002-7138-9805
Kenneth Siu Ho Chok http://orcid.org/0000-0001-7921-3807
Funding Agency and Grant Number
Corresponding Author Kenneth Siu Ho Chok, FRCS (Ed), Associate Professor, Department of Surgery, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong , Hong Kong, China. chok6275@hku.hk
Key Words Hepatocellular carcinoma; Recurrence; Liver transplantation
Core Tip We propose a multi-disciplinary management algorithm for recurrent hepatocellular carcinoma after liver transplantation. The combination of a mammalian target of rapamycin inhibitor with a reduced calcineurin inhibitor can be considered. Staging is performed to differentiate between disseminated recurrence and oligo-recurrence. In patients with disseminated recurrence, sorafenib may confer survival benefits but is associated with significant toxicity. Oligo-recurrence encompasses recurrent disease that is limited in number and location so that loco-regional treatments convey disease control and survival benefits. Intra-hepatic and extra-hepatic oligo-recurrences can be managed with surgical resection, ablative therapy or regional treatments depending on the disease status.
Publish Date 2018-12-07 03:57
Citation Au KP, Chok KSH. Multidisciplinary approach for post-liver transplant recurrence of hepatocellular carcinoma: A proposed management algorithm. World J Gastroenterol 2018; 24(45): 5081-5094
URL http://www.wjgnet.com/1007-9327/full/v24/i45/5081.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i45.5081
Full Article (PDF) WJG-24-5081.pdf
Full Article (Word) WJG-24-5081.doc
Manuscript File 41832-Review.docx
Answering Reviewers 41832-Answering reviewers.pdf
Audio Core Tip 41832-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 41832-Conflict-of-interest statement.pdf
Copyright License Agreement 41832-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 41832-Language certificate.pdf
Peer-review Report 41832-Peer-review(s).pdf
Scientific Misconduct Check 41832-Scientific misconduct check.pdf
Scientific Editor Work List 41832-Scientific editor work list.pdf